Caenorhabditis elegans PIEZO channel coordinates multiple reproductive tissues to govern ovulation

Caenorhabditis elegans PIEZO channel coordinates multiple reproductive tissues to govern ovulation

PIEZO1 and PIEZO2 are newly identified mechanosensitive ion channels that exhibit a preference for calcium in response to mechanical stimuli. In this study, we discovered the vital roles of pezo-1, the sole PIEZO ortholog in Caenorhabditiselegans, in regulating reproduction. A number of deletion all...

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Bibliographic Details
Main Authors: Xiaofei Bai, Jeff Bouffard, Avery Lord, Katherine Brugman, Paul W Sternberg, Erin J Cram, Andy Golden
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
PIEZO
disease modeling
calcium signaling
ovulation
spermatheca
sperm navigation
Online Access:https://elifesciences.org/articles/53603

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