Higher PD-L1 Immunohistochemical Detection Signal in Frozen Compared to Matched Paraffin-Embedded Formalin-Fixed Tissues

Higher PD-L1 Immunohistochemical Detection Signal in Frozen Compared to Matched Paraffin-Embedded Formalin-Fixed Tissues

Purpose: Response to anti-PD-L1/PD-1 immunotherapy correlates with PD-L1 expression in breast cancer. However, the prevalence of PD-L1 positive breast cancer is variable, which could be due to differences in the population/cohort of patients tested or the preservation/detection technology used. To i...

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Bibliographic Details
Main Authors: Hazem Ghebeh, Fatmah A. Mansour, Dilek Colak, Akram A. Alfuraydi, Amal A. Al-Thubiti, Dorota Monies, Monther Al-Alwan, Taher Al-Tweigeri, Asma Tulbah
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Antibodies
Subjects:
PD-L1
formalin
FFPE
frozen
immunohistochemistry
breast cancer
Online Access:https://www.mdpi.com/2073-4468/10/3/24

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