Biodegradable germanium electronics for integrated biosensing of physiological signals
Abstract Transient electronics that can disappear or degrade via physical disintegration or chemical reaction over a pre-defined operational period provide essential for their applications in implantable bioelectronics due to the complete elimination of the second surgical extraction. However, the d...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-07-01
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| Series: | npj Flexible Electronics |
| Online Access: | https://doi.org/10.1038/s41528-022-00196-2 |
| _version_ | 1818509990150799360 |
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| author | Haonan Zhao Zhongying Xue Xiaozhong Wu Zhihuan Wei Qiuyu Guo Miao Xu Chunyan Qu Chunyu You Yongfeng Mei Miao Zhang Zengfeng Di Qinglei Guo |
| author_facet | Haonan Zhao Zhongying Xue Xiaozhong Wu Zhihuan Wei Qiuyu Guo Miao Xu Chunyan Qu Chunyu You Yongfeng Mei Miao Zhang Zengfeng Di Qinglei Guo |
| author_sort | Haonan Zhao |
| collection | DOAJ |
| description | Abstract Transient electronics that can disappear or degrade via physical disintegration or chemical reaction over a pre-defined operational period provide essential for their applications in implantable bioelectronics due to the complete elimination of the second surgical extraction. However, the dissolution of commonly utilized bioresorbable materials often accompanies hydrogen production, which may cause potential or irreparable harm to the human body. This paper introduces germanium nanomembrane-based bioresorbable electronic sensors, where the chemical dissolution of all utilized materials in biofluidic theoretically have no gaseous products. In particular, the superior electronic transport of germanium enables the demonstrated bioresorbable electronic sensors to successfully distinguish the crosstalk of different physiological signals, such as temperature and strain, suggesting the significant prospect for the construction of dual or multi-parameter biosensors. Systematical studies reveal the gauge factor and temperature coefficient of resistance comparable to otherwise similar devices with gaseous products during their dissolution. |
| first_indexed | 2024-12-10T22:53:01Z |
| format | Article |
| id | doaj.art-e6724330207148118d470af720d93504 |
| institution | Directory Open Access Journal |
| issn | 2397-4621 |
| language | English |
| last_indexed | 2024-12-10T22:53:01Z |
| publishDate | 2022-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Flexible Electronics |
| spelling | doaj.art-e6724330207148118d470af720d935042022-12-22T01:30:22ZengNature Portfolionpj Flexible Electronics2397-46212022-07-016111010.1038/s41528-022-00196-2Biodegradable germanium electronics for integrated biosensing of physiological signalsHaonan Zhao0Zhongying Xue1Xiaozhong Wu2Zhihuan Wei3Qiuyu Guo4Miao Xu5Chunyan Qu6Chunyu You7Yongfeng Mei8Miao Zhang9Zengfeng Di10Qinglei Guo11School of Microelectronics, Center of Nanoelectronics, Shandong UniversityState Key Laboratory of Functional Materials for Informatics, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of SciencesSchool of Microelectronics, Center of Nanoelectronics, Shandong UniversitySchool of Microelectronics, Center of Nanoelectronics, Shandong UniversityDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong UniversityDepartment of Hematology, Qilu Hospital, Cheeloo College of Medicine, Shandong UniversityDepartment of Materials Science, International Institute for Intelligent Nanorobots and Nanosystems, Fudan UniversityDepartment of Materials Science, International Institute for Intelligent Nanorobots and Nanosystems, Fudan UniversityDepartment of Materials Science, International Institute for Intelligent Nanorobots and Nanosystems, Fudan UniversityState Key Laboratory of Functional Materials for Informatics, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of SciencesState Key Laboratory of Functional Materials for Informatics, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of SciencesSchool of Microelectronics, Center of Nanoelectronics, Shandong UniversityAbstract Transient electronics that can disappear or degrade via physical disintegration or chemical reaction over a pre-defined operational period provide essential for their applications in implantable bioelectronics due to the complete elimination of the second surgical extraction. However, the dissolution of commonly utilized bioresorbable materials often accompanies hydrogen production, which may cause potential or irreparable harm to the human body. This paper introduces germanium nanomembrane-based bioresorbable electronic sensors, where the chemical dissolution of all utilized materials in biofluidic theoretically have no gaseous products. In particular, the superior electronic transport of germanium enables the demonstrated bioresorbable electronic sensors to successfully distinguish the crosstalk of different physiological signals, such as temperature and strain, suggesting the significant prospect for the construction of dual or multi-parameter biosensors. Systematical studies reveal the gauge factor and temperature coefficient of resistance comparable to otherwise similar devices with gaseous products during their dissolution.https://doi.org/10.1038/s41528-022-00196-2 |
| spellingShingle | Haonan Zhao Zhongying Xue Xiaozhong Wu Zhihuan Wei Qiuyu Guo Miao Xu Chunyan Qu Chunyu You Yongfeng Mei Miao Zhang Zengfeng Di Qinglei Guo Biodegradable germanium electronics for integrated biosensing of physiological signals npj Flexible Electronics |
| title | Biodegradable germanium electronics for integrated biosensing of physiological signals |
| title_full | Biodegradable germanium electronics for integrated biosensing of physiological signals |
| title_fullStr | Biodegradable germanium electronics for integrated biosensing of physiological signals |
| title_full_unstemmed | Biodegradable germanium electronics for integrated biosensing of physiological signals |
| title_short | Biodegradable germanium electronics for integrated biosensing of physiological signals |
| title_sort | biodegradable germanium electronics for integrated biosensing of physiological signals |
| url | https://doi.org/10.1038/s41528-022-00196-2 |
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