PINK1 restrains periodontitis-induced bone loss by preventing osteoclast mitophagy impairment

The oral colonization of periodontal pathogens onto gingival tissues establishes hypoxic microenvironment, often disrupting periodontal homeostasis in conjunction with oxidative stress. The association between reactive oxygen species (ROS) and osteolytic periodontitis have been suggested by recent s...

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Bibliographic Details
Main Authors: Ji Sun Jang, Seo Jin Hong, Shenzheng Mo, Min Kyung Kim, Yong-Gun Kim, Youngkyun Lee, Hong-Hee Kim
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S221323172300424X