A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of Life
<i>Background and Objectives</i>: Previous studies have assessed the association between arterial stiffness and depressive and anxiety symptoms, but the results were inconsistent. We aimed to conduct a cross-sectional study to assess the relationship between arterial stiffness, depressiv...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Medicina |
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| Online Access: | https://www.mdpi.com/1648-9144/59/3/477 |
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| author | Tae-Kyung Yoo Seunghee Lee Soo-Young Hwang Curie Ahn Saejong Park Jong-Young Lee |
| author_facet | Tae-Kyung Yoo Seunghee Lee Soo-Young Hwang Curie Ahn Saejong Park Jong-Young Lee |
| author_sort | Tae-Kyung Yoo |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Previous studies have assessed the association between arterial stiffness and depressive and anxiety symptoms, but the results were inconsistent. We aimed to conduct a cross-sectional study to assess the relationship between arterial stiffness, depressive and anxiety symptoms, and quality of life. <i>Materials and Methods</i>: We analyzed the 2014–2015 Korea Institute of Sport Science Fitness Standards project data. Brachial-ankle pulse wave velocity (baPWV) was measured to assess arterial stiffness. High baPWV was defined as a baPWV higher than 1400 cm/s. Participants completed Beck’s depressive symptoms inventory (BDI), Beck’s anxiety symptoms inventory (BAI), and the World Health Organization’s Quality of Life Questionnaire (WHOQOL-Bref). We performed a logistic regression analysis by adjusting confounding factors and used the inverse probability of treatment weighting (IPTW) method. <i>Results</i>: 1936 participants were included in the analysis (men 43.9%, median age 47). Participants with a high baPWV had higher odds of depressive symptoms compared to those with a normal baPWV (aOR 1.920, 95% CI 1.062–3.472, <i>p</i> = 0.031; IPTW OR 2.637, 95% CI 1.219–5.704, <i>p</i> = 0.014). In addition, baPWV was significantly associated with depressive symptoms in the IPTW model in men but not in women (OR 2.497, 95% CI 1.004–6.207, <i>p</i> = 0.049). High baPWV was not associated with anxiety symptoms in all models, but it was associated with poor QOL in women (OR 4.561, 95% CI 1.465–14.199, <i>p</i> = 0.009). <i>Conclusions</i>: High baPWV was associated with higher odds of depressive symptoms, especially in men. Our study suggests a modest association between arterial stiffness and depressive symptoms in Korean adults. |
| first_indexed | 2024-03-11T06:12:51Z |
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| id | doaj.art-e67b6f1efe784b9887ed5762770fc9d8 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T06:12:51Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
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| series | Medicina |
| spelling | doaj.art-e67b6f1efe784b9887ed5762770fc9d82023-11-17T12:31:11ZengMDPI AGMedicina1010-660X1648-91442023-02-0159347710.3390/medicina59030477A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of LifeTae-Kyung Yoo0Seunghee Lee1Soo-Young Hwang2Curie Ahn3Saejong Park4Jong-Young Lee5Department of Medicine, MetroWest Medical Center, Framingham, MA 01702, USADepartment of Physical Education, Korea University, Seoul 02841, Republic of KoreaHarvard T.H. Chan School of Public Health, Boston, MA 02115, USADepartment of Medicine, MetroWest Medical Center, Framingham, MA 01702, USADivision of Sports Science, Korea Institute of Sport Science, Seoul 01794, Republic of KoreaDivision of Cardiology, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul 03181, Republic of Korea<i>Background and Objectives</i>: Previous studies have assessed the association between arterial stiffness and depressive and anxiety symptoms, but the results were inconsistent. We aimed to conduct a cross-sectional study to assess the relationship between arterial stiffness, depressive and anxiety symptoms, and quality of life. <i>Materials and Methods</i>: We analyzed the 2014–2015 Korea Institute of Sport Science Fitness Standards project data. Brachial-ankle pulse wave velocity (baPWV) was measured to assess arterial stiffness. High baPWV was defined as a baPWV higher than 1400 cm/s. Participants completed Beck’s depressive symptoms inventory (BDI), Beck’s anxiety symptoms inventory (BAI), and the World Health Organization’s Quality of Life Questionnaire (WHOQOL-Bref). We performed a logistic regression analysis by adjusting confounding factors and used the inverse probability of treatment weighting (IPTW) method. <i>Results</i>: 1936 participants were included in the analysis (men 43.9%, median age 47). Participants with a high baPWV had higher odds of depressive symptoms compared to those with a normal baPWV (aOR 1.920, 95% CI 1.062–3.472, <i>p</i> = 0.031; IPTW OR 2.637, 95% CI 1.219–5.704, <i>p</i> = 0.014). In addition, baPWV was significantly associated with depressive symptoms in the IPTW model in men but not in women (OR 2.497, 95% CI 1.004–6.207, <i>p</i> = 0.049). High baPWV was not associated with anxiety symptoms in all models, but it was associated with poor QOL in women (OR 4.561, 95% CI 1.465–14.199, <i>p</i> = 0.009). <i>Conclusions</i>: High baPWV was associated with higher odds of depressive symptoms, especially in men. Our study suggests a modest association between arterial stiffness and depressive symptoms in Korean adults.https://www.mdpi.com/1648-9144/59/3/477arterial stiffnessdepressive symptomsanxiety symptomsquality of life |
| spellingShingle | Tae-Kyung Yoo Seunghee Lee Soo-Young Hwang Curie Ahn Saejong Park Jong-Young Lee A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of Life Medicina arterial stiffness depressive symptoms anxiety symptoms quality of life |
| title | A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of Life |
| title_full | A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of Life |
| title_fullStr | A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of Life |
| title_full_unstemmed | A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of Life |
| title_short | A Cross-Sectional Investigation of the Association between Arterial Stiffness and Depressive Symptoms, Anxiety Symptoms, and Quality of Life |
| title_sort | cross sectional investigation of the association between arterial stiffness and depressive symptoms anxiety symptoms and quality of life |
| topic | arterial stiffness depressive symptoms anxiety symptoms quality of life |
| url | https://www.mdpi.com/1648-9144/59/3/477 |
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