3,3-Disubstituted 3,4-Dihydro-1,2,4-benzotriazines: Chemistry, Biological Activity, and Affinity to Sigma Receptors

3,3-Disubstituted 3,4-Dihydro-1,2,4-benzotriazines: Chemistry, Biological Activity, and Affinity to Sigma Receptors

By reducing the 2-nitrophenylhydrazone of cyclohexanone with sodium dithionite, an unexpected yellow compound was obtained instead of the corresponding colorless amino derivative. Many years later, the structure of this compound, namely, cyclohexane-3-spiro-3,4-dihydro-1,2,4-benzotriazine, was demon...

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Bibliographic Details
Main Authors:	Fabio Sparatore, Anna Sparatore
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Series:	Molecules
Subjects:	3,4-dihydro-1,2,4-benzotriazines 2-nitro-phenylhydrazone reduction sigma receptor ligands antihypertensive activity anti-inflammatory activity diuretic activity
Online Access:	https://www.mdpi.com/1420-3049/29/1/132

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