Sarcoidosis and Primary Biliary Cholangitis- An Overlap
Primary Biliary Cholangitis (PBC) is a chronic progressive autoimmune cholestatic liver disease. Sarcoidosis is a multisystem chronic granulomatous disease. Both diseases are known to affect the liver causing granulomas. Sarcoidosis commonly involves the skin while PBC is associated with autoimmun...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2021-07-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/15101/49016_CE[Ra1]_F[IK]_PF1(SC_RK)_PN(KM).pdf |
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| author | Akshatha Manohar CA Jayashankar Nithin Kumar Prakash Bhanu Prathima Shivaji Rao |
| author_facet | Akshatha Manohar CA Jayashankar Nithin Kumar Prakash Bhanu Prathima Shivaji Rao |
| author_sort | Akshatha Manohar |
| collection | DOAJ |
| description | Primary Biliary Cholangitis (PBC) is a chronic progressive autoimmune cholestatic liver disease. Sarcoidosis is a multisystem
chronic granulomatous disease. Both diseases are known to affect the liver causing granulomas. Sarcoidosis commonly involves
the skin while PBC is associated with autoimmune skin disorders. Diagnosis of PBC requires biochemical, serological and
histological confirmation. Steroids are used in the treatment of sarcoidosis. The role of steroids in the treatment of PBC is not
completely established. In this case report, authors present the case of a 31-years-old female diagnosed as sarcoidosis based on
granulomatous lesions in skin biopsy with concurrent PBC diagnosed on basis of serology and liver biopsy |
| first_indexed | 2024-12-17T20:45:43Z |
| format | Article |
| id | doaj.art-e6891ba0da364b1fbc59cb637482de90 |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-17T20:45:43Z |
| publishDate | 2021-07-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-e6891ba0da364b1fbc59cb637482de902022-12-21T21:33:10ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-07-011507131510.7860/JCDR/2021/49016:15101Sarcoidosis and Primary Biliary Cholangitis- An OverlapAkshatha Manohar0CA Jayashankar1 Nithin Kumar2Prakash Bhanu3Prathima Shivaji Rao4Junior Resident, Department of General Medicine, Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, IndiaProfessor and Head, Department of General Medicine, Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, IndiaSenior Resident, Department of Gastroenterology, Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, IndiaProfessor, Department of Dermatology, Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, IndiaProfessor and Head, Department of Pathology, Vydehi Institute of Medical Sciences and Research Centre, Bengaluru, Karnataka, IndiaPrimary Biliary Cholangitis (PBC) is a chronic progressive autoimmune cholestatic liver disease. Sarcoidosis is a multisystem chronic granulomatous disease. Both diseases are known to affect the liver causing granulomas. Sarcoidosis commonly involves the skin while PBC is associated with autoimmune skin disorders. Diagnosis of PBC requires biochemical, serological and histological confirmation. Steroids are used in the treatment of sarcoidosis. The role of steroids in the treatment of PBC is not completely established. In this case report, authors present the case of a 31-years-old female diagnosed as sarcoidosis based on granulomatous lesions in skin biopsy with concurrent PBC diagnosed on basis of serology and liver biopsyhttps://jcdr.net/articles/PDF/15101/49016_CE[Ra1]_F[IK]_PF1(SC_RK)_PN(KM).pdfautoimmune liver diseasechronic granulomatous diseaseliver granulomaskin plaque |
| spellingShingle | Akshatha Manohar CA Jayashankar Nithin Kumar Prakash Bhanu Prathima Shivaji Rao Sarcoidosis and Primary Biliary Cholangitis- An Overlap Journal of Clinical and Diagnostic Research autoimmune liver disease chronic granulomatous disease liver granuloma skin plaque |
| title | Sarcoidosis and Primary Biliary Cholangitis- An Overlap |
| title_full | Sarcoidosis and Primary Biliary Cholangitis- An Overlap |
| title_fullStr | Sarcoidosis and Primary Biliary Cholangitis- An Overlap |
| title_full_unstemmed | Sarcoidosis and Primary Biliary Cholangitis- An Overlap |
| title_short | Sarcoidosis and Primary Biliary Cholangitis- An Overlap |
| title_sort | sarcoidosis and primary biliary cholangitis an overlap |
| topic | autoimmune liver disease chronic granulomatous disease liver granuloma skin plaque |
| url | https://jcdr.net/articles/PDF/15101/49016_CE[Ra1]_F[IK]_PF1(SC_RK)_PN(KM).pdf |
| work_keys_str_mv | AT akshathamanohar sarcoidosisandprimarybiliarycholangitisanoverlap AT cajayashankar sarcoidosisandprimarybiliarycholangitisanoverlap AT nithinkumar sarcoidosisandprimarybiliarycholangitisanoverlap AT prakashbhanu sarcoidosisandprimarybiliarycholangitisanoverlap AT prathimashivajirao sarcoidosisandprimarybiliarycholangitisanoverlap |