Pulse Wave Analysis in Obese Children with and without Metabolic Syndrome
INTRODUCTION: To compare pulse wave analysis (PWA) of obese children with and without metabolic syndrome (MS) with healthy, non-obese children and to evaluate the association between PWA findings and additional risk factors present in children with MS and obesity. METHODS: From the obese patients e...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Yayincilik
2023-12-01
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| Series: | JCRPE |
| Subjects: | |
| Online Access: | https://jcrpe.org/jvi.aspx?pdir=jcrpe&plng=eng&un=JCRPE-54889&look4= |
| _version_ | 1797449596187705344 |
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| author | Cemaliye Başaran Gökçen Erfidan Özgür Özdemir-Şimşek Seçil Arslansoyu-Çamlar Demet Alaygut Fatma Mutlubaş Cem Karadeniz Bumin Nuri Dündar Belde Kasap-Demir |
| author_facet | Cemaliye Başaran Gökçen Erfidan Özgür Özdemir-Şimşek Seçil Arslansoyu-Çamlar Demet Alaygut Fatma Mutlubaş Cem Karadeniz Bumin Nuri Dündar Belde Kasap-Demir |
| author_sort | Cemaliye Başaran |
| collection | DOAJ |
| description | INTRODUCTION: To compare pulse wave analysis (PWA) of obese children with and without metabolic syndrome (MS) with healthy, non-obese children and to evaluate the association between PWA findings and additional risk factors present in children with MS and obesity.
METHODS: From the obese patients examined between June 2019 and June 2021, 41 patients with MS, 36 obese patients without MS, and 34 healthy non-obese children of similar age and gender were evaluated retrospectively. Anthropometric measurements, biochemical evaluation, 24-hour ambulatory blood pressure (BP) measurement (ABPM), left ventricular mass index (LVMI) and PWA measurements were compared.
RESULTS: When the three groups were compared, weight standard deviation score (SDS), height SDS and body mass index SDS were all significantly higher in the MS group (p<0.05). The following measurements were significantly higher in both MS and non-MS obese patients compared to the control group: from ABPM measures, the systolic and mean arterial pressure BP SDSs load; from PWA, the night central systolic BP, 24-hour, day and night pulse pressure values and 24-hour, day and night pulse wave velocity (PWV) rates; and from cardiac evaluations, the LVMI and relative wall thickness measurements (all p<0.05). Furthermore, the 24-hour and daytime central systolic (cSBP) and diastolic BP (cDBP) values were significantly different between the three groups, being the highest in the MS group (p<0.05).
DISCUSSION AND CONCLUSION: Obesity causes higher office, ambulatory and central BP, PWV and LVMI. However our results suggest that additional risk factors associated with MS do not contribute to these parameters, except for 24-hour and daytime cSBP and cDBP values. |
| first_indexed | 2024-03-09T14:27:19Z |
| format | Article |
| id | doaj.art-e68a8ae45e9549da8ff95d78d4ad6b7c |
| institution | Directory Open Access Journal |
| issn | 1308-5727 1308-5735 |
| language | English |
| last_indexed | 2024-03-09T14:27:19Z |
| publishDate | 2023-12-01 |
| publisher | Galenos Yayincilik |
| record_format | Article |
| series | JCRPE |
| spelling | doaj.art-e68a8ae45e9549da8ff95d78d4ad6b7c2023-11-28T06:43:33ZengGalenos YayincilikJCRPE1308-57271308-57352023-12-0115439740510.4274/jcrpe.galenos.2023.2022-10-21Pulse Wave Analysis in Obese Children with and without Metabolic SyndromeCemaliye Başaran0https://orcid.org/0000-0002-6422-7998Gökçen Erfidan1https://orcid.org/0000-0001-5217-5847Özgür Özdemir-Şimşek2https://orcid.org/0000-0001-5705-7452Seçil Arslansoyu-Çamlar3https://orcid.org/0000-0002-2402-0722Demet Alaygut4https://orcid.org/0000-0002-2164-4652Fatma Mutlubaş5https://orcid.org/0000-0001-9392-4832Cem Karadeniz6https://orcid.org/0000-0003-0529-2391Bumin Nuri Dündar7https://orcid.org/0000-0002-7506-061XBelde Kasap-Demir8https://orcid.org/0000-0002-5456-3509University Health Sciences Turkey, İzmir Tepecik Training and Research Hospital, Clinic of Pediatrics, Division of Nephrology, İzmir, TurkeyUniversity Health Sciences Turkey, İzmir Tepecik Training and Research Hospital, Clinic of Pediatrics, Division of Nephrology, İzmir, TurkeyUniversity Health Sciences Turkey, İzmir Tepecik Training and Research Hospital, Clinic of Pediatrics, Division of Nephrology, İzmir, TurkeyUniversity Health Sciences Turkey, İzmir Faculty of Medicine, Department of Pediatrics, Division of Nephrology, İzmir, TurkeyUniversity Health Sciences Turkey, İzmir Faculty of Medicine, Department of Pediatrics, Division of Nephrology, İzmir, TurkeyUniversity Health Sciences Turkey, İzmir Faculty of Medicine, Department of Pediatrics, Division of Nephrology, İzmir, Turkeyİzmir Katip Çelebi University Faculty of Medicine, Department of Pediatrics, Division of Cardiology, İzmir, Turkeyİzmir Katip Çelebi University Faculty of Medicine, Department of Pediatrics, Division of Endocrinology, İzmir, TurkeyUniversity Health Sciences Turkey, İzmir Tepecik Training and Research Hospital, Clinic of Pediatrics, Division of Nephrology, İzmir, TurkeyINTRODUCTION: To compare pulse wave analysis (PWA) of obese children with and without metabolic syndrome (MS) with healthy, non-obese children and to evaluate the association between PWA findings and additional risk factors present in children with MS and obesity. METHODS: From the obese patients examined between June 2019 and June 2021, 41 patients with MS, 36 obese patients without MS, and 34 healthy non-obese children of similar age and gender were evaluated retrospectively. Anthropometric measurements, biochemical evaluation, 24-hour ambulatory blood pressure (BP) measurement (ABPM), left ventricular mass index (LVMI) and PWA measurements were compared. RESULTS: When the three groups were compared, weight standard deviation score (SDS), height SDS and body mass index SDS were all significantly higher in the MS group (p<0.05). The following measurements were significantly higher in both MS and non-MS obese patients compared to the control group: from ABPM measures, the systolic and mean arterial pressure BP SDSs load; from PWA, the night central systolic BP, 24-hour, day and night pulse pressure values and 24-hour, day and night pulse wave velocity (PWV) rates; and from cardiac evaluations, the LVMI and relative wall thickness measurements (all p<0.05). Furthermore, the 24-hour and daytime central systolic (cSBP) and diastolic BP (cDBP) values were significantly different between the three groups, being the highest in the MS group (p<0.05). DISCUSSION AND CONCLUSION: Obesity causes higher office, ambulatory and central BP, PWV and LVMI. However our results suggest that additional risk factors associated with MS do not contribute to these parameters, except for 24-hour and daytime cSBP and cDBP values.https://jcrpe.org/jvi.aspx?pdir=jcrpe&plng=eng&un=JCRPE-54889&look4=childrenpulse wave analysismetabolic syndromeobesity |
| spellingShingle | Cemaliye Başaran Gökçen Erfidan Özgür Özdemir-Şimşek Seçil Arslansoyu-Çamlar Demet Alaygut Fatma Mutlubaş Cem Karadeniz Bumin Nuri Dündar Belde Kasap-Demir Pulse Wave Analysis in Obese Children with and without Metabolic Syndrome JCRPE children pulse wave analysis metabolic syndrome obesity |
| title | Pulse Wave Analysis in Obese Children with and without Metabolic Syndrome |
| title_full | Pulse Wave Analysis in Obese Children with and without Metabolic Syndrome |
| title_fullStr | Pulse Wave Analysis in Obese Children with and without Metabolic Syndrome |
| title_full_unstemmed | Pulse Wave Analysis in Obese Children with and without Metabolic Syndrome |
| title_short | Pulse Wave Analysis in Obese Children with and without Metabolic Syndrome |
| title_sort | pulse wave analysis in obese children with and without metabolic syndrome |
| topic | children pulse wave analysis metabolic syndrome obesity |
| url | https://jcrpe.org/jvi.aspx?pdir=jcrpe&plng=eng&un=JCRPE-54889&look4= |
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