Current understanding of iberiotoxin-resistant BK channels in the nervous system

While most large-conductance, calcium- and voltage-activated potassium channels (BK or Maxi-K type) are blocked by the scorpion venom iberiotoxin, the so-called type II subtype has the property of toxin resistance. This property is uniquely mediated by channel assembly with one member of the BK acce...

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Bibliographic Details
Main Authors: Bin eWang, David B Jaffe, Robert eBrenner
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00382/full