Current understanding of iberiotoxin-resistant BK channels in the nervous system

Current understanding of iberiotoxin-resistant BK channels in the nervous system

While most large-conductance, calcium- and voltage-activated potassium channels (BK or Maxi-K type) are blocked by the scorpion venom iberiotoxin, the so-called type II subtype has the property of toxin resistance. This property is uniquely mediated by channel assembly with one member of the BK acce...

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Bibliographic Details
Main Authors:	Bin eWang, David B Jaffe, Robert eBrenner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2014-10-01
Series:	Frontiers in Physiology
Subjects:	Membrane Proteins calcium-activated potassium channel BK channel MaxiK KCNMA1 KCNMB4
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphys.2014.00382/full

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