INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION
Aim. To study the relationship of 24-hour BP patterns in patients with AH resistant to drug treatment and structural-functional changes in heart before and after sympathetic denervation of the kidneys.Material and methods. The study included 53 patients (25 women and 28 men) with a diagnosis of II s...
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2015-04-01
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| Series: | Российский кардиологический журнал |
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| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/278 |
| _version_ | 1826561399286923264 |
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| author | V. A. Lichikaki S. E. Pekarsky V. R. Mordovin R. S. Karpov |
| author_facet | V. A. Lichikaki S. E. Pekarsky V. R. Mordovin R. S. Karpov |
| author_sort | V. A. Lichikaki |
| collection | DOAJ |
| description | Aim. To study the relationship of 24-hour BP patterns in patients with AH resistant to drug treatment and structural-functional changes in heart before and after sympathetic denervation of the kidneys.Material and methods. The study included 53 patients (25 women and 28 men) with a diagnosis of II stage hypertension, resistant to drug therapy. Mean quantity of continuous drug compounds taking is 4,09±1,16. baseline office SBP for all patients — 176,3±19,9 mmHg, by ABPM — 158,2±14,5 mmHg, left ventricle myocardium mass (LVMM) — 275,3±91,9 g. All patients under the informed consent conditions underwent renal denervation with endovascular catheter. We analyzed the data from 46 patients (87%), studied in 6 months after ablation. All patients before and after the procedure underwent 24-hour BP monitoring and echocardiography Results. Depending on the grade of hypotensive effect after denervation all patients were divided into groups of responders (35 persons), non-responders (11 patients). In responders we found higher level of office SBP and DBP at baseline as variability of BP. In 6 months after ablation variability of SBP and DBP, level of mean daily SBP and DBP, and office values of SBP and DBP were significantly higher than in non-responders. Comparing ABPM parameters with the patterns of echocardiographic changes of the heart there were no significant differences between the groups of responders and non-responders.Conclusion. The data obtained makes evident that the decrease of hypertrophy of the left ventricle in the patients with resistant AH by sympathetic renal denervation is predefined at first by a grade of mean daily levels of BP by the data of 24-hour monitoring and also significantly by the dynamics of 24-hour BP index. |
| first_indexed | 2024-04-09T20:50:26Z |
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| id | doaj.art-e68b0bdb6d64427a89120659a7b3b01c |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:31:33Z |
| publishDate | 2015-04-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-e68b0bdb6d64427a89120659a7b3b01c2025-03-02T11:42:36Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202015-04-0104232610.15829/1560-4071-2015-4-23-26278INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSIONV. A. Lichikaki0S. E. Pekarsky1V. R. Mordovin2R. S. Karpov3FSBI SRI of Cardiology SD RAMS, Tomsk, Russia.FSBI SRI of Cardiology SD RAMS, Tomsk, Russia.FSBI SRI of Cardiology SD RAMS, Tomsk, Russia.FSBI SRI of Cardiology SD RAMS, Tomsk, Russia.Aim. To study the relationship of 24-hour BP patterns in patients with AH resistant to drug treatment and structural-functional changes in heart before and after sympathetic denervation of the kidneys.Material and methods. The study included 53 patients (25 women and 28 men) with a diagnosis of II stage hypertension, resistant to drug therapy. Mean quantity of continuous drug compounds taking is 4,09±1,16. baseline office SBP for all patients — 176,3±19,9 mmHg, by ABPM — 158,2±14,5 mmHg, left ventricle myocardium mass (LVMM) — 275,3±91,9 g. All patients under the informed consent conditions underwent renal denervation with endovascular catheter. We analyzed the data from 46 patients (87%), studied in 6 months after ablation. All patients before and after the procedure underwent 24-hour BP monitoring and echocardiography Results. Depending on the grade of hypotensive effect after denervation all patients were divided into groups of responders (35 persons), non-responders (11 patients). In responders we found higher level of office SBP and DBP at baseline as variability of BP. In 6 months after ablation variability of SBP and DBP, level of mean daily SBP and DBP, and office values of SBP and DBP were significantly higher than in non-responders. Comparing ABPM parameters with the patterns of echocardiographic changes of the heart there were no significant differences between the groups of responders and non-responders.Conclusion. The data obtained makes evident that the decrease of hypertrophy of the left ventricle in the patients with resistant AH by sympathetic renal denervation is predefined at first by a grade of mean daily levels of BP by the data of 24-hour monitoring and also significantly by the dynamics of 24-hour BP index.https://russjcardiol.elpub.ru/jour/article/view/278resistant hypertensionrenal denervationleft ventricle hypertrophy. |
| spellingShingle | V. A. Lichikaki S. E. Pekarsky V. R. Mordovin R. S. Karpov INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION Российский кардиологический журнал resistant hypertension renal denervation left ventricle hypertrophy. |
| title | INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
| title_full | INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
| title_fullStr | INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
| title_full_unstemmed | INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
| title_short | INFLUENCE OF 24-HOUR BLOOD PRESSURE PATTERNS ON STRUCTURAL AND FUNCTIONAL CHANGES OF THE HEART IN PATIENTS WITH RESISTANT ARTERIAL HYPERTENSION |
| title_sort | influence of 24 hour blood pressure patterns on structural and functional changes of the heart in patients with resistant arterial hypertension |
| topic | resistant hypertension renal denervation left ventricle hypertrophy. |
| url | https://russjcardiol.elpub.ru/jour/article/view/278 |
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