Systematic functional analysis of the Com pilus in Streptococcus sanguinis: a minimalistic type 4 filament dedicated to DNA uptake in monoderm bacteria

Systematic functional analysis of the Com pilus in Streptococcus sanguinis: a minimalistic type 4 filament dedicated to DNA uptake in monoderm bacteria

ABSTRACTType 4 filaments (T4F) are a superfamily of versatile nanomachines, ubiquitous in prokaryotes, which use conserved multi-protein machineries to assemble and operate filamentous polymers of type 4 pilins. In the best-studied T4F, these machineries are complex, which has posed challenges to un...

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Bibliographic Details
Main Authors: Jeremy Mom, Iman Chouikha, Odile Valette, Laetitia Pieulle, Vladimir Pelicic
Format: Article
Language:English
Published: American Society for Microbiology 2024-01-01
Series:mBio
Subjects:
type 4 pili
type 4 filaments
pilus assembly
genetic competence
Online Access:https://journals.asm.org/doi/10.1128/mbio.02667-23

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