Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and Reliability

Semi-quantitative elastography is a promising imaging technique to evaluate tissue stiffness differences, providing data regarding relative stiffness differences between two targets. The aims of this study were to assess the validity, inter-examiner reliability and variability of semi-quantitative e...

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Main Authors: Juan Antonio Valera-Calero, César Fernández-de-las-Peñas, Tomás Fernández-Rodríguez, José Luis Arias-Buría, Umut Varol, Gracia María Gallego-Sendarrubias
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Applied Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3417/11/19/9247
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author Juan Antonio Valera-Calero
César Fernández-de-las-Peñas
Tomás Fernández-Rodríguez
José Luis Arias-Buría
Umut Varol
Gracia María Gallego-Sendarrubias
author_facet Juan Antonio Valera-Calero
César Fernández-de-las-Peñas
Tomás Fernández-Rodríguez
José Luis Arias-Buría
Umut Varol
Gracia María Gallego-Sendarrubias
author_sort Juan Antonio Valera-Calero
collection DOAJ
description Semi-quantitative elastography is a promising imaging technique to evaluate tissue stiffness differences, providing data regarding relative stiffness differences between two targets. The aims of this study were to assess the validity, inter-examiner reliability and variability of semi-quantitative elastography for calculating strain ratios (SR) in a homogeneous gel phantom in different locations within the image. A diagnostic accuracy study was performed in a homogeneous stiffness phantom. Four examiners participated (two novice and two experienced). Each examiner assessed the SR in two locations. Difference between examiners, variability of measurements, SR error and absolute error, mean error of the measurements and coefficient of variation were calculated. The agreement between examiners, validity and variability of measurements were higher in the central area than the lateral areas of the images. Thus, the experience of the examiner was relevant for the concordance of the measurements in the lateral areas of the images (SR difference of 0.14 ± 0.05; <i>p</i> < 0.001), but not for the central area (SR difference of 0.05 ± 0.02; <i>p</i> > 0.05). Our data suggested that semi-quantitative elastography is an accurate tool for assessing small magnitude stiffness differences within the same image in central areas, but the experience of the examiner is a determinant factor.
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spelling doaj.art-e68eb33107f54010ba211b62b1c75b982023-11-22T15:49:55ZengMDPI AGApplied Sciences2076-34172021-10-011119924710.3390/app11199247Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and ReliabilityJuan Antonio Valera-Calero0César Fernández-de-las-Peñas1Tomás Fernández-Rodríguez2José Luis Arias-Buría3Umut Varol4Gracia María Gallego-Sendarrubias5Department of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, Villanueva de la Cañada, 28692 Madrid, SpainDepartment of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, 28922 Madrid, SpainDepartment of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, Villanueva de la Cañada, 28692 Madrid, SpainDepartment of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Universidad Rey Juan Carlos, Alcorcón, 28922 Madrid, SpainIE School of Human Sciences and Technology, IE Business School, 28006 Madrid, SpainDepartment of Physiotherapy, Faculty of Health, Universidad Camilo José Cela, Villanueva de la Cañada, 28692 Madrid, SpainSemi-quantitative elastography is a promising imaging technique to evaluate tissue stiffness differences, providing data regarding relative stiffness differences between two targets. The aims of this study were to assess the validity, inter-examiner reliability and variability of semi-quantitative elastography for calculating strain ratios (SR) in a homogeneous gel phantom in different locations within the image. A diagnostic accuracy study was performed in a homogeneous stiffness phantom. Four examiners participated (two novice and two experienced). Each examiner assessed the SR in two locations. Difference between examiners, variability of measurements, SR error and absolute error, mean error of the measurements and coefficient of variation were calculated. The agreement between examiners, validity and variability of measurements were higher in the central area than the lateral areas of the images. Thus, the experience of the examiner was relevant for the concordance of the measurements in the lateral areas of the images (SR difference of 0.14 ± 0.05; <i>p</i> < 0.001), but not for the central area (SR difference of 0.05 ± 0.02; <i>p</i> > 0.05). Our data suggested that semi-quantitative elastography is an accurate tool for assessing small magnitude stiffness differences within the same image in central areas, but the experience of the examiner is a determinant factor.https://www.mdpi.com/2076-3417/11/19/9247ultrasound imagingelastographyvalidityreliabilitycalibration
spellingShingle Juan Antonio Valera-Calero
César Fernández-de-las-Peñas
Tomás Fernández-Rodríguez
José Luis Arias-Buría
Umut Varol
Gracia María Gallego-Sendarrubias
Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and Reliability
Applied Sciences
ultrasound imaging
elastography
validity
reliability
calibration
title Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and Reliability
title_full Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and Reliability
title_fullStr Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and Reliability
title_full_unstemmed Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and Reliability
title_short Influence of Examiners’ Experience and Region of Interest Location on Semiquantitative Elastography Validity and Reliability
title_sort influence of examiners experience and region of interest location on semiquantitative elastography validity and reliability
topic ultrasound imaging
elastography
validity
reliability
calibration
url https://www.mdpi.com/2076-3417/11/19/9247
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