Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications
Metabolomics is a rapidly growing field that aims to understand the complex metabolic pathways involved in health and disease. Liquid chromatography mass spectrometry (LC-MS) based untargeted metabolomics has emerged as a powerful tool for investigating the metabolic changes associated with various...
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| Format: | Article |
| Language: | English |
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De Gruyter
2024-01-01
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| Series: | Türk Biyokimya Dergisi |
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| Online Access: | https://doi.org/10.1515/tjb-2023-0095 |
| _version_ | 1827330768397926400 |
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| author | Doğan Halef Okan |
| author_facet | Doğan Halef Okan |
| author_sort | Doğan Halef Okan |
| collection | DOAJ |
| description | Metabolomics is a rapidly growing field that aims to understand the complex metabolic pathways involved in health and disease. Liquid chromatography mass spectrometry (LC-MS) based untargeted metabolomics has emerged as a powerful tool for investigating the metabolic changes associated with various diseases, and for identifying potential biomarkers for early disease detection and treatment monitoring. This review provides a comprehensive overview of LC-MS based untargeted metabolomics and its clinical applications. |
| first_indexed | 2024-03-07T16:21:13Z |
| format | Article |
| id | doaj.art-e692e59d0def4570af8166dcf5da062f |
| institution | Directory Open Access Journal |
| issn | 1303-829X |
| language | English |
| last_indexed | 2024-03-07T16:21:13Z |
| publishDate | 2024-01-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj.art-e692e59d0def4570af8166dcf5da062f2024-03-04T07:29:49ZengDe GruyterTürk Biyokimya Dergisi1303-829X2024-01-0149111410.1515/tjb-2023-0095Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applicationsDoğan Halef Okan0Department of Biochemistry, School of Medicine, University of Sivas Cumhuriyet, Sivas, TürkiyeMetabolomics is a rapidly growing field that aims to understand the complex metabolic pathways involved in health and disease. Liquid chromatography mass spectrometry (LC-MS) based untargeted metabolomics has emerged as a powerful tool for investigating the metabolic changes associated with various diseases, and for identifying potential biomarkers for early disease detection and treatment monitoring. This review provides a comprehensive overview of LC-MS based untargeted metabolomics and its clinical applications.https://doi.org/10.1515/tjb-2023-0095untargeted metabolomicslc-msclinical applicationsbiomarkerpersonalized medicine |
| spellingShingle | Doğan Halef Okan Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications Türk Biyokimya Dergisi untargeted metabolomics lc-ms clinical applications biomarker personalized medicine |
| title | Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications |
| title_full | Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications |
| title_fullStr | Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications |
| title_full_unstemmed | Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications |
| title_short | Metabolomics: a review of liquid chromatography mass spectrometry-based methods and clinical applications |
| title_sort | metabolomics a review of liquid chromatography mass spectrometry based methods and clinical applications |
| topic | untargeted metabolomics lc-ms clinical applications biomarker personalized medicine |
| url | https://doi.org/10.1515/tjb-2023-0095 |
| work_keys_str_mv | AT doganhalefokan metabolomicsareviewofliquidchromatographymassspectrometrybasedmethodsandclinicalapplications |