Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation.

Postprandial apoE isoform and conformational changes associated with VLDL lipolysis products modulate monocyte inflammation.

Postprandial hyperlipemia, characterized by increased circulating very low-density lipoproteins (VLDL) and circulating lipopolysaccharide (LPS), has been proposed as a mechanism of vascular injury. Our goal was to examine the interactions between postprandial lipoproteins, LPS, and apoE3 and apoE4 o...

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Bibliographic Details
Main Authors: Laura J den Hartigh, Robin Altman, Romobia Hutchinson, Jitka Petrlova, Madhu S Budamagunta, Sarada D Tetali, Jens O Lagerstedt, John C Voss, John C Rutledge
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3509065?pdf=render

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