Inhibitory Action of Antidiabetic Drugs on the Free Radical Production by the Rod Outer Segment Ectopic Aerobic Metabolism
Rod outer segments (OS) express the F<sub>o</sub>F<sub>1</sub>-ATP synthase and the respiratory chain, conducting an ectopic aerobic metabolism that produces free radicals in vitro. Diabetic retinopathy, a leading cause of vision loss, is associated with oxidative stress in t...
Main Authors: | Silvia Ravera, Federico Caicci, Paolo Degan, Davide Maggi, Lucia Manni, Alessandra Puddu, Massimo Nicolò, Carlo E. Traverso, Isabella Panfoli |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-11-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/9/11/1133 |
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