B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies

B cells in esophago-gastric adenocarcinoma are highly differentiated, organize in tertiary lymphoid structures and produce tumor-specific antibodies

Tumor-infiltrating lymphocytes (TILs) are correlated to prognosis of several kinds of cancer. Most studies focused on T cells, while the role of tumor-associated B cells (TABs) has only recently gained more attention. TABs contain subpopulations with distinct functions, potentially promoting or inhi...

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Main Authors: Hans A. Schlößer, Martin Thelen, Axel Lechner, Kerstin Wennhold, Maria A. Garcia-Marquez, Sacha I. Rothschild, Elena Staib, Thomas Zander, Dirk Beutner, Birgit Gathof, Ramona Gilles, Engin Cukuroglu, Jonathan Göke, Alexander Shimabukuro-Vornhagen, Uta Drebber, Alexander Quaas, Christiane J. Bruns, Arnulf H. Hölscher, Michael S. Von Bergwelt-Baildon
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:OncoImmunology
Subjects:
plasma cells
tumor associated antigen
antibody
esophageal cancer
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1512458

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