Long non-coding RNA LUCAT1/miR-5582-3p/TCF7L2 axis regulates breast cancer stemness via Wnt/β-catenin pathway

Long non-coding RNA LUCAT1/miR-5582-3p/TCF7L2 axis regulates breast cancer stemness via Wnt/β-catenin pathway

Abstract Background The mechanism underlying breast cancer stem cell (BCSCs) characteristics remains to be fully elucidated. Accumulating evidence implies that long noncoding RNAs (lncRNAs) play a pivotal role in regulating BCSCs stemness. Methods LncRNA LUCAT1 expression was assessed in breast canc...

Full description

Bibliographic Details
Main Authors:	Ang Zheng, Xinyue Song, Lin Zhang, Lin Zhao, Xiaoyun Mao, Minjie Wei, Feng Jin
Format:	Article
Language:	English
Published:	BMC 2019-07-01
Series:	Journal of Experimental & Clinical Cancer Research
Subjects:	Breast cancer Stemness LUCAT1 miR-5582-3p Wnt/β-catenin signaling pathway
Online Access:	http://link.springer.com/article/10.1186/s13046-019-1315-8

Similar Items

Characterization of a Novel LUCAT1/miR-4316/VEGF-A Axis in Metastasis and Glycolysis of Lung Adenocarcinoma
by: Lishui Wang, et al.
Published: (2022-05-01)

LncRNA LUCAT1/miR-181a-5p axis promotes proliferation and invasion of breast cancer via targeting KLF6 and KLF15
by: Yun Liu, et al.
Published: (2020-09-01)

LncRNA LUCAT1 contributes to cell proliferation and migration in human pancreatic ductal adenocarcinoma via sponging miR‐539
by: Yongjun Nai, et al.
Published: (2020-01-01)

Sevoflurane Inhibited Osteosarcoma Cell Proliferation And Invasion Via Targeting miR-203/WNT2B/Wnt/β-Catenin Axis
by: Chen M, et al.
Published: (2019-11-01)

Evaluating the effects of curcumin nano-chitosan on miR-221 and miR-222 expression and Wnt/β-catenin pathways in MCF-7, MDA-MB-231 and SKBR3 cell lines
by: Touba Eslaminejad, et al.
Published: (2024-02-01)

RETRACTED ARTICLE: MiR-200c/FUT4 axis prevents the proliferation of colon cancer cells by downregulating the Wnt/β-catenin pathway
by: Jinchun Cong, et al.
Published: (2021-01-01)

Icariin attenuates the tumor growth by targeting miR-1-3p/TNKS2/Wnt/β-catenin signaling axis in ovarian cancer
by: Yanjin Fu, et al.
Published: (2022-09-01)

MEG3 targets miR-184 and Wnt/β-catenin and modulates properties of osteosarcoma
by: Liang Li, et al.
Published: (2020-06-01)

Deciphering the role of Wnt/β-catenin and miR-214 in knee osteoarthritis: molecular and clinical insights
by: Waad A. Samman, et al.
Published: (2025-02-01)

Selective Wnt/β-Catenin Pathway Activation Concomitant With Sustained Overexpression of miR-21 is Responsible for Aristolochic Acid-Induced AKI-to-CKD Transition
by: Qing Kuang, et al.
Published: (2021-05-01)

MiR‐26b suppresses hepatocellular carcinoma development by negatively regulating ZNRD1 and Wnt/β‐catenin signaling
by: Xiaobo Hu, et al.
Published: (2019-12-01)

Upregulation of long intergenic non-coding RNA LINC00326 inhibits non-small cell lung carcinoma progression by blocking Wnt/β-catenin pathway through modulating the miR-657/dickkopf WNT signaling pathway inhibitor 2 axis
by: Yingqian Zhang, et al.
Published: (2023-02-01)

miR-140-y targets TCF4 to regulate the Wnt signaling pathway and promote embryonic feather follicle development in Hungarian white goose
by: Jingyun Ma, et al.
Published: (2024-04-01)

Rotavirus-Mediated Suppression of miRNA-192 Family and miRNA-181a Activates Wnt/β-Catenin Signaling Pathway: An In Vitro Study
by: Anwesha Banerjee, et al.
Published: (2022-03-01)

miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt–β-catenin pathway
by: Qiang Liu, et al.
Published: (2019-08-01)

Upregulation of CCT-3 Induces Breast Cancer Cell Proliferation Through miR-223 Competition and Wnt/β-Catenin Signaling Pathway Activation
by: Hongbo Qu, et al.
Published: (2020-09-01)

SNHG29 regulates miR-223-3p/CTNND1 axis to promote glioblastoma progression via Wnt/β-catenin signaling pathway
by: Lizhang Han, et al.
Published: (2019-12-01)

PITX2 enhances progression of lung adenocarcinoma by transcriptionally regulating WNT3A and activating Wnt/β-catenin signaling pathway
by: Jing Luo, et al.
Published: (2019-04-01)

Mir-195-5p targets Smad7 regulation of the Wnt/β-catenin pathway to promote osteogenic differentiation of vascular smooth muscle cells
by: Wei Lin, et al.
Published: (2024-04-01)

RETRACTED: Corrigendum: Upregulation of CCT-3 Induces Breast Cancer Cell Proliferation Through miR-223 Competition and Wnt/b-Catenin Signaling Pathway Activation
by: Hongbo Qu, et al.
Published: (2022-05-01)

MiR-455-3p inhibits gastric cancer progression by repressing Wnt/β-catenin signaling through binding to ARMC8
by: Ting Zhan, et al.
Published: (2023-07-01)

MiR-129-5p Inhibits Proliferation and Invasion of Chondrosarcoma Cells by Regulating SOX4/Wnt/β-Catenin Signaling Pathway
by: Peng Zhang, et al.
Published: (2017-05-01)

Circ‐EIF3I facilitates proliferation, migration, and invasion of lung cancer via regulating the activity of Wnt/β‐catenin pathway through the miR‐1253/NOVA2 axis
by: Tao Chen, et al.
Published: (2022-11-01)

MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia
by: Bing Liu, et al.
Published: (2019-05-01)

Exosomal miR92a Promotes Cytarabine Resistance in Myelodysplastic Syndromes by Activating Wnt/β-catenin Signal Pathway
by: Hongjiao Li, et al.
Published: (2022-10-01)

LINC01189-miR-586-ZEB1 feedback loop regulates breast cancer progression through Wnt/β-catenin signaling pathway
by: Di Zhang, et al.
Published: (2021-09-01)

Hypoxic BMSC-derived exosomal miR-210-3p promotes progression of triple-negative breast cancer cells via NFIX-Wnt/β-catenin signaling axis
by: Meng Wang, et al.
Published: (2025-01-01)

The Long Non-Coding RNA CRNDE Promotes Colorectal Carcinoma Progression by Competitively Binding miR-217 with TCF7L2 and Enhancing the Wnt/β-Catenin Signaling Pathway
by: Bo Yu, et al.
Published: (2017-05-01)

MiR-452 promotes an aggressive colorectal cancer phenotype by regulating a Wnt/β-catenin positive feedback loop
by: Tingting Li, et al.
Published: (2018-09-01)

Upregulation of miR-501-5p activates the wnt/β-catenin signaling pathway and enhances stem cell-like phenotype in gastric cancer
by: Dongmei Fan, et al.
Published: (2016-11-01)

LINC00482 sponged miR-2467-3p to promote bone metastasis of prostate cancer through activating Wnt/β-catenin signaling pathway
by: Shiyao Liao, et al.
Published: (2023-08-01)

miR-489-3p promotes malignant progression of non-small cell lung cancer through the inactivation of Wnt/β-catenin signaling pathway via regulating USP48
by: Pei Zhang, et al.
Published: (2022-04-01)

Mechanism of action of miR-15a-5p and miR-152-3p in paraquat-induced pulmonary fibrosis through Wnt/β-catenin signaling mediation
by: Dong Liu, et al.
Published: (2024-07-01)

Single-cell transcriptomics and Mendelian randomization reveal LUCAT1’s role in right-sided colorectal cancer risk
by: Zhihao Shang, et al.
Published: (2024-04-01)

hsa_circ_0000285 sponging miR-582-3p promotes neuroblastoma progression by regulating the Wnt/β-catenin signaling pathway
by: Du Jun, et al.
Published: (2023-07-01)

miR-634 inhibits human vascular smooth muscle cell proliferation and migration in hypertension through Wnt4/β-catenin pathway
by: Ligang Niu, et al.
Published: (2021-08-01)

Circ_0051079 silencing inhibits the malignant phenotypes of osteosarcoma cells by the TRIM66/Wnt/β-catenin pathway in a miR-625-5p-dependent manner
by: Weilin Wang, et al.
Published: (2022-08-01)

Mir-381-3p aggravates ovariectomy-induced osteoporosis by inhibiting osteogenic differentiation through targeting KLF5/Wnt/β-catenin signaling pathway
by: Yingwei Zhao, et al.
Published: (2024-08-01)

Aspirin ameliorates lung cancer by targeting the miR‐98/WNT1 axis
by: Huizhu Gan, et al.
Published: (2019-04-01)

CMTM7 inhibits breast cancer progression by regulating Wnt/β-catenin signaling
by: Zhao-Hui Chen, et al.
Published: (2023-02-01)