Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden
While prenatal exposure to ambient air pollution has been shown to be associated with reduced birth weight, there is substantial heterogeneity across studies, and few epidemiological studies have utilized source-specific exposure data. The aim of the present study was, therefore, to investigate the...
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MDPI AG
2022-07-01
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| Series: | Toxics |
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| Online Access: | https://www.mdpi.com/2305-6304/10/7/366 |
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| author | Festina Balidemaj Erin Flanagan Ebba Malmqvist Ralf Rittner Karin Källén Daniel Oudin Åström Anna Oudin |
| author_facet | Festina Balidemaj Erin Flanagan Ebba Malmqvist Ralf Rittner Karin Källén Daniel Oudin Åström Anna Oudin |
| author_sort | Festina Balidemaj |
| collection | DOAJ |
| description | While prenatal exposure to ambient air pollution has been shown to be associated with reduced birth weight, there is substantial heterogeneity across studies, and few epidemiological studies have utilized source-specific exposure data. The aim of the present study was, therefore, to investigate the associations between local, source-specific exposure to fine particulate matter (PM<sub>2.5</sub>) during pregnancy and birth weight. An administrative cohort comprising 40,245 singleton births from 2000 to 2009 in Scania, Sweden, was combined with data on relevant covariates. Investigated sources of PM<sub>2.5</sub> included all local sources together as well as tailpipe exhaust, vehicle wear-and-tear, and small-scale residential heating separately. The relationships between these exposures, represented as interquartile range (IQR) increases, and birth weight (continuous) and low birth weight (LBW; <2500 g) were analyzed in crude and adjusted models. Each local PM<sub>2.5</sub> source investigated was associated with reduced birth weight; average decreases varied by source (12–34 g). Only small-scale residential heating was clearly associated with LBW (adjusted odds ratio: 1.14 (95% confidence interval: 1.04–1.26) per IQR increase). These results add to existing evidence that prenatal exposure to ambient air pollution disrupts fetal growth and suggest that PM<sub>2.5</sub> from both vehicles and small-scale residential heating may reduce birth weight. |
| first_indexed | 2024-03-09T12:56:23Z |
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| id | doaj.art-e69cf69a292f44b1b90438f9f8dda792 |
| institution | Directory Open Access Journal |
| issn | 2305-6304 |
| language | English |
| last_indexed | 2024-03-09T12:56:23Z |
| publishDate | 2022-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxics |
| spelling | doaj.art-e69cf69a292f44b1b90438f9f8dda7922023-11-30T22:00:47ZengMDPI AGToxics2305-63042022-07-0110736610.3390/toxics10070366Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern SwedenFestina Balidemaj0Erin Flanagan1Ebba Malmqvist2Ralf Rittner3Karin Källén4Daniel Oudin Åström5Anna Oudin6Division of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 222 42 Lund, SwedenDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 222 42 Lund, SwedenDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 222 42 Lund, SwedenDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 222 42 Lund, SwedenDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 222 42 Lund, SwedenDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 222 42 Lund, SwedenDivision of Occupational and Environmental Medicine, Department of Laboratory Medicine, Lund University, 222 42 Lund, SwedenWhile prenatal exposure to ambient air pollution has been shown to be associated with reduced birth weight, there is substantial heterogeneity across studies, and few epidemiological studies have utilized source-specific exposure data. The aim of the present study was, therefore, to investigate the associations between local, source-specific exposure to fine particulate matter (PM<sub>2.5</sub>) during pregnancy and birth weight. An administrative cohort comprising 40,245 singleton births from 2000 to 2009 in Scania, Sweden, was combined with data on relevant covariates. Investigated sources of PM<sub>2.5</sub> included all local sources together as well as tailpipe exhaust, vehicle wear-and-tear, and small-scale residential heating separately. The relationships between these exposures, represented as interquartile range (IQR) increases, and birth weight (continuous) and low birth weight (LBW; <2500 g) were analyzed in crude and adjusted models. Each local PM<sub>2.5</sub> source investigated was associated with reduced birth weight; average decreases varied by source (12–34 g). Only small-scale residential heating was clearly associated with LBW (adjusted odds ratio: 1.14 (95% confidence interval: 1.04–1.26) per IQR increase). These results add to existing evidence that prenatal exposure to ambient air pollution disrupts fetal growth and suggest that PM<sub>2.5</sub> from both vehicles and small-scale residential heating may reduce birth weight.https://www.mdpi.com/2305-6304/10/7/366ambient air pollutionfine particulate matterlocal air pollutionsource-specific exposuretraffic-related air pollutionresidential burning |
| spellingShingle | Festina Balidemaj Erin Flanagan Ebba Malmqvist Ralf Rittner Karin Källén Daniel Oudin Åström Anna Oudin Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden Toxics ambient air pollution fine particulate matter local air pollution source-specific exposure traffic-related air pollution residential burning |
| title | Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden |
| title_full | Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden |
| title_fullStr | Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden |
| title_full_unstemmed | Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden |
| title_short | Prenatal Exposure to Locally Emitted Air Pollutants Is Associated with Birth Weight: An Administrative Cohort Study from Southern Sweden |
| title_sort | prenatal exposure to locally emitted air pollutants is associated with birth weight an administrative cohort study from southern sweden |
| topic | ambient air pollution fine particulate matter local air pollution source-specific exposure traffic-related air pollution residential burning |
| url | https://www.mdpi.com/2305-6304/10/7/366 |
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