Characterizing genetic interactions in human disease association studies using statistical epistasis networks

Characterizing genetic interactions in human disease association studies using statistical epistasis networks

<p>Abstract</p> <p>Background</p> <p>Epistasis is recognized ubiquitous in the genetic architecture of complex traits such as disease susceptibility. Experimental studies in model organisms have revealed extensive evidence of biological interactions among genes. Meanwhi...

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Bibliographic Details
Main Authors: Andrew Angeline S, Kiralis Jeff W, Sinnott-Armstrong Nicholas A, Hu Ting, Karagas Margaret R, Moore Jason H
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/364

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