Free radical destruction of hydroxyl-containing amino acids
А new way of the free radical ROS- and HOCl-induced destruction of serine, threonine, and their peptide derivatives due to the nitrogen-centered radicals formation and their subsequent decomposition with the side chain elimination has been established. It has been shown that substances with reducing...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Belarusian |
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Belarusian State University
2019-02-01
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| Series: | Журнал Белорусского государственного университета: Химия |
| Subjects: | |
| Online Access: | https://journals.bsu.by/index.php/chemistry/article/view/1257 |
| _version_ | 1819276311962583040 |
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| author | Anastasia A. Sladkova Irina P. Edimecheva Anna A. Sosnovskaya Oleg I. Shadyro |
| author_facet | Anastasia A. Sladkova Irina P. Edimecheva Anna A. Sosnovskaya Oleg I. Shadyro |
| author_sort | Anastasia A. Sladkova |
| collection | DOAJ |
| description | А new way of the free radical ROS- and HOCl-induced destruction of serine, threonine, and their peptide derivatives due to the nitrogen-centered radicals formation and their subsequent decomposition with the side chain elimination has been established. It has been shown that substances with reducing properties are inhibitors of this process, while oxygen does not affect the probability of its occurrence. The data obtained are relevant for the development of novel approaches to the search for effective free radical processes regulators. |
| first_indexed | 2024-12-23T23:38:13Z |
| format | Article |
| id | doaj.art-e69fa923c5f04358b75d5d052e4c5785 |
| institution | Directory Open Access Journal |
| issn | 2520-257X 2617-3980 |
| language | Belarusian |
| last_indexed | 2024-12-23T23:38:13Z |
| publishDate | 2019-02-01 |
| publisher | Belarusian State University |
| record_format | Article |
| series | Журнал Белорусского государственного университета: Химия |
| spelling | doaj.art-e69fa923c5f04358b75d5d052e4c57852022-12-21T17:25:48ZbelBelarusian State UniversityЖурнал Белорусского государственного университета: Химия2520-257X2617-39802019-02-01131310.33581/2520-257X-2019-1-3-131257Free radical destruction of hydroxyl-containing amino acidsAnastasia A. Sladkova0Irina P. Edimecheva1Anna A. Sosnovskaya2Oleg I. Shadyro3Belarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus; Research Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusResearch Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusResearch Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusBelarusian State University, 4 Niezaliežnasci Avenue, Minsk 220030, Belarus; Research Institute for Physical Chemical Problems, Belarusian State University, 14 Lieninhradskaja Street, Minsk 220006, BelarusА new way of the free radical ROS- and HOCl-induced destruction of serine, threonine, and their peptide derivatives due to the nitrogen-centered radicals formation and their subsequent decomposition with the side chain elimination has been established. It has been shown that substances with reducing properties are inhibitors of this process, while oxygen does not affect the probability of its occurrence. The data obtained are relevant for the development of novel approaches to the search for effective free radical processes regulators.https://journals.bsu.by/index.php/chemistry/article/view/1257serinethreoninefree radical reactionscarbon skeleton destructionbiochemical reactions |
| spellingShingle | Anastasia A. Sladkova Irina P. Edimecheva Anna A. Sosnovskaya Oleg I. Shadyro Free radical destruction of hydroxyl-containing amino acids Журнал Белорусского государственного университета: Химия serine threonine free radical reactions carbon skeleton destruction biochemical reactions |
| title | Free radical destruction of hydroxyl-containing amino acids |
| title_full | Free radical destruction of hydroxyl-containing amino acids |
| title_fullStr | Free radical destruction of hydroxyl-containing amino acids |
| title_full_unstemmed | Free radical destruction of hydroxyl-containing amino acids |
| title_short | Free radical destruction of hydroxyl-containing amino acids |
| title_sort | free radical destruction of hydroxyl containing amino acids |
| topic | serine threonine free radical reactions carbon skeleton destruction biochemical reactions |
| url | https://journals.bsu.by/index.php/chemistry/article/view/1257 |
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