Significance of interleukin-33 and its related cytokines in patients with breast cancers

Significance of interleukin-33 and its related cytokines in patients with breast cancers

Interleukin-33 (IL-33) is a recently identified cytokine, an important member of the IL-1 family. IL-33 binds to its receptor ST2 to induce type 2 cytokines and exert both pro-inflammatory and protective functions in host defense and disease. Murine breast carcinoma models suggest disruption of ST2...

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Bibliographic Details
Main Authors: Jing eLiu, Jia-Xin eShen, Jia-Lin eHu, Wen-He eHuang, Guo-Jun eZhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Immunology
Subjects:
Cytokines
Immunosuppression
breast cancer
ST2/ST2L
interleukin-33
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00141/full

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