Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan
In Japan, monovalent vaccine against mumps virus (MuV) infection was shifted to a voluntary basis vaccination due to the incidences of aseptic meningitis in the past. According to an analysis of a total of 409 participants aged 18–20 years, overall vaccination coverage rate was 48%. The mean anti-Mu...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2021-09-01
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| Series: | Human Vaccines & Immunotherapeutics |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/21645515.2021.1913967 |
| _version_ | 1797674514790744064 |
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| author | Hiraku Sasaki Tomoko Fukunaga Ai Asano Kansuke Yamanaka Kota Oikawa Nobuto Shibata |
| author_facet | Hiraku Sasaki Tomoko Fukunaga Ai Asano Kansuke Yamanaka Kota Oikawa Nobuto Shibata |
| author_sort | Hiraku Sasaki |
| collection | DOAJ |
| description | In Japan, monovalent vaccine against mumps virus (MuV) infection was shifted to a voluntary basis vaccination due to the incidences of aseptic meningitis in the past. According to an analysis of a total of 409 participants aged 18–20 years, overall vaccination coverage rate was 48%. The mean anti-MuV IgG antibody titer of participants with medical history and more than two times vaccination was significantly higher than that in those without a medical history and unvaccinated and single vaccination, respectively. Seropositivity against MuV infection was >50% regardless of the number of vaccinations. Although these results suggest that seropositivity may persist due to asymptomatic infection, it is necessary to implement either a high vaccine coverage or routine vaccination for prevention of periodic mumps epidemics. |
| first_indexed | 2024-03-11T22:01:10Z |
| format | Article |
| id | doaj.art-e6a0a98c52a54141b998a06043302e42 |
| institution | Directory Open Access Journal |
| issn | 2164-5515 2164-554X |
| language | English |
| last_indexed | 2024-03-11T22:01:10Z |
| publishDate | 2021-09-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Human Vaccines & Immunotherapeutics |
| spelling | doaj.art-e6a0a98c52a54141b998a06043302e422023-09-25T11:19:18ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2021-09-011793153315510.1080/21645515.2021.19139671913967Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in JapanHiraku Sasaki0Tomoko Fukunaga1Ai Asano2Kansuke Yamanaka3Kota Oikawa4Nobuto Shibata5Juntendo UniversityJuntendo UniversityJuntendo UniversityJuntendo UniversityJuntendo UniversityJuntendo Tokyo Koto Geriatric Medical CenterIn Japan, monovalent vaccine against mumps virus (MuV) infection was shifted to a voluntary basis vaccination due to the incidences of aseptic meningitis in the past. According to an analysis of a total of 409 participants aged 18–20 years, overall vaccination coverage rate was 48%. The mean anti-MuV IgG antibody titer of participants with medical history and more than two times vaccination was significantly higher than that in those without a medical history and unvaccinated and single vaccination, respectively. Seropositivity against MuV infection was >50% regardless of the number of vaccinations. Although these results suggest that seropositivity may persist due to asymptomatic infection, it is necessary to implement either a high vaccine coverage or routine vaccination for prevention of periodic mumps epidemics.http://dx.doi.org/10.1080/21645515.2021.1913967mumpsmuvigg antibody titervaccination |
| spellingShingle | Hiraku Sasaki Tomoko Fukunaga Ai Asano Kansuke Yamanaka Kota Oikawa Nobuto Shibata Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan Human Vaccines & Immunotherapeutics mumps muv igg antibody titer vaccination |
| title | Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan |
| title_full | Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan |
| title_fullStr | Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan |
| title_full_unstemmed | Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan |
| title_short | Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan |
| title_sort | seroprevalence of anti mumps virus igg antibody titer and voluntary mumps vaccination coverage in young adults in japan |
| topic | mumps muv igg antibody titer vaccination |
| url | http://dx.doi.org/10.1080/21645515.2021.1913967 |
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