Brain trust
This narrative describes a personal journey that led to the discovery of a profound connection between microbial symbionts and oxytocin. Pivotal oxytocin discoveries began to emerge in 2011 while this researcher’s multidisciplinary team explored gut microbial priming of the immune system and perinat...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | Comprehensive Psychoneuroendocrinology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666497623000462 |
| _version_ | 1797398530524971008 |
|---|---|
| author | Susan E. Erdman |
| author_facet | Susan E. Erdman |
| author_sort | Susan E. Erdman |
| collection | DOAJ |
| description | This narrative describes a personal journey that led to the discovery of a profound connection between microbial symbionts and oxytocin. Pivotal oxytocin discoveries began to emerge in 2011 while this researcher’s multidisciplinary team explored gut microbial priming of the immune system and perinatal health. Inspired by oxytocin's role in early life events of milk release, neural connections, and social bonding, the team hypothesized a symbiotic relationship between microbes and oxytocin. Scientific experiments demonstrated that specific milk-borne microbes boosted oxytocin levels through a vagus nerve-mediated gut-brain pathway, affecting immune functions and wound healing capacity in the host animal. The exploration then expanded to microbial impacts on reproductive fitness, body weight, and even mental health. Overarching hypotheses envisioned a nurturing symbiosis promoting survival and societal advancement. Ultimately, this oxytocin-mediated partnership between microbes and mammals is portrayed as a harmonious legacy of neurological stability, empathy, and universal wisdom, transcending generations. The author's personal journey underscores the beauty and inspiration found in her scientific exploration. |
| first_indexed | 2024-03-09T01:26:49Z |
| format | Article |
| id | doaj.art-e6a5f20e45834e8b92620dd6f34c9302 |
| institution | Directory Open Access Journal |
| issn | 2666-4976 |
| language | English |
| last_indexed | 2024-03-09T01:26:49Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Comprehensive Psychoneuroendocrinology |
| spelling | doaj.art-e6a5f20e45834e8b92620dd6f34c93022023-12-10T06:18:08ZengElsevierComprehensive Psychoneuroendocrinology2666-49762023-11-0116100212Brain trustSusan E. Erdman0Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USAThis narrative describes a personal journey that led to the discovery of a profound connection between microbial symbionts and oxytocin. Pivotal oxytocin discoveries began to emerge in 2011 while this researcher’s multidisciplinary team explored gut microbial priming of the immune system and perinatal health. Inspired by oxytocin's role in early life events of milk release, neural connections, and social bonding, the team hypothesized a symbiotic relationship between microbes and oxytocin. Scientific experiments demonstrated that specific milk-borne microbes boosted oxytocin levels through a vagus nerve-mediated gut-brain pathway, affecting immune functions and wound healing capacity in the host animal. The exploration then expanded to microbial impacts on reproductive fitness, body weight, and even mental health. Overarching hypotheses envisioned a nurturing symbiosis promoting survival and societal advancement. Ultimately, this oxytocin-mediated partnership between microbes and mammals is portrayed as a harmonious legacy of neurological stability, empathy, and universal wisdom, transcending generations. The author's personal journey underscores the beauty and inspiration found in her scientific exploration.http://www.sciencedirect.com/science/article/pii/S2666497623000462SymbioticSymbiontProbioticL. reuteriGut-brain-immuneVagus nerve |
| spellingShingle | Susan E. Erdman Brain trust Comprehensive Psychoneuroendocrinology Symbiotic Symbiont Probiotic L. reuteri Gut-brain-immune Vagus nerve |
| title | Brain trust |
| title_full | Brain trust |
| title_fullStr | Brain trust |
| title_full_unstemmed | Brain trust |
| title_short | Brain trust |
| title_sort | brain trust |
| topic | Symbiotic Symbiont Probiotic L. reuteri Gut-brain-immune Vagus nerve |
| url | http://www.sciencedirect.com/science/article/pii/S2666497623000462 |
| work_keys_str_mv | AT susaneerdman braintrust |