MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONE

Abstract Medical treatment using misoprostol has been recommended as an alternative to surgical evacuation for missed miscarriage in the first trimester in order to avoid anesthesia, surgical operation and hospitalization. Our aim is to assess the efficacy and safety of vaginal misoprostol in out-p...

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Main Authors: Zainab Baqer Abdullah, Nada H Al-Jassim
Format: Article
Language:English
Published: university of basrah 2016-12-01
Series:Basrah Journal of Surgery
Subjects:
Online Access:https://bjsrg.uobasrah.edu.iq/article_116622_c5723c00e4f2ad3041cfde415e0999ad.pdf
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author Zainab Baqer Abdullah
Nada H Al-Jassim
author_facet Zainab Baqer Abdullah
Nada H Al-Jassim
author_sort Zainab Baqer Abdullah
collection DOAJ
description Abstract Medical treatment using misoprostol has been recommended as an alternative to surgical evacuation for missed miscarriage in the first trimester in order to avoid anesthesia, surgical operation and hospitalization. Our aim is to assess the efficacy and safety of vaginal misoprostol in out-patient management of early miscarriages. This prospective study included patients with missed miscarriage of ≤10 weeks gestation. The protocol used 800 microgram of misoprostol on day 1 at clinic, followed by another dose of 800 microgram of misoprostol on day 2 if miscarriage was not complete. The included 150 patients, had missed miscarriage or anembryonic pregnancies. The success rate defined has complete miscarriage without need for surgical evacuation and without shortterm complications. Complete expulsion occurred within 2 days in 90.7% of cases. There were 14 patients needed surgical evacuations and admission to hospital (5 for method failure, 2 for incomplete miscarriage and 7 according to women decision). No one required blood transfusion. In conclusion, it is possible to use misoprostol as an out-patient treatment, since it gives satisfactory efficacy and is sufficiently safe.
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spelling doaj.art-e6aa39f852b24e3fa76107eefc1b54f72022-12-22T01:06:49Zenguniversity of basrahBasrah Journal of Surgery1683-35892409-501X2016-12-0122210010410.33762/bsurg.2016.116622116622MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONEZainab Baqer AbdullahNada H Al-JassimAbstract Medical treatment using misoprostol has been recommended as an alternative to surgical evacuation for missed miscarriage in the first trimester in order to avoid anesthesia, surgical operation and hospitalization. Our aim is to assess the efficacy and safety of vaginal misoprostol in out-patient management of early miscarriages. This prospective study included patients with missed miscarriage of ≤10 weeks gestation. The protocol used 800 microgram of misoprostol on day 1 at clinic, followed by another dose of 800 microgram of misoprostol on day 2 if miscarriage was not complete. The included 150 patients, had missed miscarriage or anembryonic pregnancies. The success rate defined has complete miscarriage without need for surgical evacuation and without shortterm complications. Complete expulsion occurred within 2 days in 90.7% of cases. There were 14 patients needed surgical evacuations and admission to hospital (5 for method failure, 2 for incomplete miscarriage and 7 according to women decision). No one required blood transfusion. In conclusion, it is possible to use misoprostol as an out-patient treatment, since it gives satisfactory efficacy and is sufficiently safe.https://bjsrg.uobasrah.edu.iq/article_116622_c5723c00e4f2ad3041cfde415e0999ad.pdfmissedmiscarriageanembryonic pregnanciesmisoprostol alone
spellingShingle Zainab Baqer Abdullah
Nada H Al-Jassim
MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONE
Basrah Journal of Surgery
missed
miscarriage
anembryonic pregnancies
misoprostol alone
title MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONE
title_full MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONE
title_fullStr MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONE
title_full_unstemmed MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONE
title_short MEDICAL TREATMENT OF EARLY MISSED MISCARRIAGE AND ANEMBRYONIC PREGNANCIES: A PROSPECTIVE STUDY OF OUTPATIENT MANAGEMENT USING MISOPROSTOL ALONE
title_sort medical treatment of early missed miscarriage and anembryonic pregnancies a prospective study of outpatient management using misoprostol alone
topic missed
miscarriage
anembryonic pregnancies
misoprostol alone
url https://bjsrg.uobasrah.edu.iq/article_116622_c5723c00e4f2ad3041cfde415e0999ad.pdf
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