Mutations in <it>ASXL1 </it>are associated with poor prognosis across the spectrum of malignant myeloid diseases

Mutations in <it>ASXL1 </it>are associated with poor prognosis across the spectrum of malignant myeloid diseases

<p>Abstract</p> <p>The <it>ASXL1 </it>gene is one of the most frequently mutated genes in malignant myeloid diseases. The ASXL1 protein belongs to protein complexes involved in the epigenetic regulation of gene expression. <it>ASXL1 </it>mutations are found...

Full description

Bibliographic Details
Main Authors: Gelsi-Boyer Véronique, Brecqueville Mandy, Devillier Raynier, Murati Anne, Mozziconacci Marie-Joelle, Birnbaum Daniel
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Journal of Hematology & Oncology
Subjects:
<it>ASXL1</it>
Gene mutations
Myeloid diseases
Online Access:http://www.jhoonline.org/content/5/1/12

Similar Items

Similar Items