Escherichia coli resistance mechanism AcrAB-TolC efflux pump interactions with commonly used antibiotics: a molecular dynamics study
Abstract While antibiotic resistance poses a threat from both Gram-positive bacteria (GPB) and Gram-negative bacteria (GNB), GNB pose a more imminent public health hazard globally. GNB are a threat to growing antibiotic resistance because of the complex makeup of the membrane. The AcrAB-TolC efflux...
Main Authors: | , , |
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Formato: | Artigo |
Idioma: | English |
Publicado: |
Nature Portfolio
2024-02-01
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Series: | Scientific Reports |
Acceso en liña: | https://doi.org/10.1038/s41598-024-52536-z |