Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung disease
Abstract Publications utilizing precision cut lung slices (PCLS) steadily increased from the 1970’s, with a significant increase in 2010, to tripling by 2023. PCLS have been used to study a vast array of pulmonary diseases and exposures to pathogens and toxicants to understand pathogenesis of diseas...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-03-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12931-024-02756-8 |
| _version_ | 1797247100462825472 |
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| author | Cynthia J. Koziol-White Reynold A. Panettieri Jr. |
| author_facet | Cynthia J. Koziol-White Reynold A. Panettieri Jr. |
| author_sort | Cynthia J. Koziol-White |
| collection | DOAJ |
| description | Abstract Publications utilizing precision cut lung slices (PCLS) steadily increased from the 1970’s, with a significant increase in 2010, to tripling by 2023. PCLS have been used to study a vast array of pulmonary diseases and exposures to pathogens and toxicants to understand pathogenesis of disease but also to examine basic cellular mechanisms that underly lung biology. This Special Issue will highlight new, exciting, and novel research using PCLS, while acknowledging the substantial fund of knowledge that has been gained using this platform. |
| first_indexed | 2024-04-24T19:53:19Z |
| format | Article |
| id | doaj.art-e6b7103fd07444f9bf13d3f50e0c0556 |
| institution | Directory Open Access Journal |
| issn | 1465-993X |
| language | English |
| last_indexed | 2024-04-24T19:53:19Z |
| publishDate | 2024-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-e6b7103fd07444f9bf13d3f50e0c05562024-03-24T12:29:55ZengBMCRespiratory Research1465-993X2024-03-012511210.1186/s12931-024-02756-8Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung diseaseCynthia J. Koziol-White0Reynold A. Panettieri Jr.1Rutgers Institute for Translational Medicine and Science, Rutgers UniversityRutgers Institute for Translational Medicine and Science, Rutgers UniversityAbstract Publications utilizing precision cut lung slices (PCLS) steadily increased from the 1970’s, with a significant increase in 2010, to tripling by 2023. PCLS have been used to study a vast array of pulmonary diseases and exposures to pathogens and toxicants to understand pathogenesis of disease but also to examine basic cellular mechanisms that underly lung biology. This Special Issue will highlight new, exciting, and novel research using PCLS, while acknowledging the substantial fund of knowledge that has been gained using this platform.https://doi.org/10.1186/s12931-024-02756-8Precision cut lung slicesRespiratory therapeuticsAirway physiology in precision cut lung slices |
| spellingShingle | Cynthia J. Koziol-White Reynold A. Panettieri Jr. Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung disease Respiratory Research Precision cut lung slices Respiratory therapeutics Airway physiology in precision cut lung slices |
| title | Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung disease |
| title_full | Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung disease |
| title_fullStr | Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung disease |
| title_full_unstemmed | Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung disease |
| title_short | Editorial for special issue—human precision cut lung slices: an Ex vivo platform for therapeutic target discovery and drug testing in lung disease |
| title_sort | editorial for special issue human precision cut lung slices an ex vivo platform for therapeutic target discovery and drug testing in lung disease |
| topic | Precision cut lung slices Respiratory therapeutics Airway physiology in precision cut lung slices |
| url | https://doi.org/10.1186/s12931-024-02756-8 |
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