Novel cyanine dye as competitive ligand for probing the drug–nucleic acid interactions

Novel cyanine dye as competitive ligand for probing the drug–nucleic acid interactions

Background: During the past decades, increasing attention has been given to elucidating the molecular details of interactions between the pharmacological agents and nucleic acids since the drug–DNA complexation may lead to impairment of DNA replication, strand breaking and mutations. A variety of te...

Full description

Bibliographic Details
Main Authors: O. Zhytniakivska, U. Tarabara, A. Kurutos, A. Zabrudska, K. Vus, V. Trusova, G. Gorbenko, T. Deligeorgiev
Format: Article
Language:English
Published: V.N. Karazin Kharkiv National University 2020-07-01
Series:Біофізичний вісник
Subjects:
trimethine cyanine dye
europium coordination complexes
rna
dna
antitumor drug
association constant
Online Access:https://periodicals.karazin.ua/biophysvisnyk/article/view/14612

Similar Items

Similar Items