Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -Iraq

Background:Bronchial asthma is a common chronic respiratory disease worldwide. Although magnesium (Mg) deficiency has been shown to play a role in exacerbation of asthma, the exact prevalence of hypomagnesaemia in asthma is not clear. Objective: To estimate the serum Mg levels in bronchial asthm...

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Main Authors: Kamaran Mahmud Saidoka, Salam Naser Zangana, Rebaz Tahir Lak
Format: Article
Language:English
Published: College of medicine/ University of Diyala 2019-10-01
Series:Diyala Journal of Medicine
Subjects:
Online Access:http://djm.uodiyala.edu.iq/index.php/djm/article/view/338
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author Kamaran Mahmud Saidoka
Salam Naser Zangana
Rebaz Tahir Lak
author_facet Kamaran Mahmud Saidoka
Salam Naser Zangana
Rebaz Tahir Lak
author_sort Kamaran Mahmud Saidoka
collection DOAJ
description Background:Bronchial asthma is a common chronic respiratory disease worldwide. Although magnesium (Mg) deficiency has been shown to play a role in exacerbation of asthma, the exact prevalence of hypomagnesaemia in asthma is not clear. Objective: To estimate the serum Mg levels in bronchial asthma patients and compare them with healthy population and to evaluate the prevalence of hypomagnesaemia among them. Patients and Methods: A cross-sectional study was carried out in the respiratory unit of Rizgary Teaching Hospital involving 80 adult patients with chronic asthma (group I) and 80 healthy adult controls (group II). Serum magnesium level was measured in all the participants. Results: Hypomagnesaemia was detected in 20% of the asthmatic patients when compared to controls (0%) (p=0.001). No significant association was detected between magnesium status and type of asthma (p= 0.59). There was a statistically significant stage-wise decline in serum levels of Mg with increase in severity of asthma (p=0.02). Patients with severe asthma had the highest prevalence of hypomagnesaemia (45.5%) in comparison to mild and moderate cases (p=0.001). No significant associations were detected between the level of magnesium and the number of medications that the patients used, corticosteroids use, and theophylline therapy (p=0.06, 0.17, and 0.08, respectively). Hypomagnesaemia was significantly correlated with the duration of asthma (p=0.04). Conclusion: Hypomagnesaemia is more prevalent in chronic asthmatics than non-asthmatics. Hypomagnesaemia was significantly correlated with severity and duration of asthma.
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spelling doaj.art-e6bc19387a48484fb467af6267bd9b8e2023-11-24T23:23:55ZengCollege of medicine/ University of DiyalaDiyala Journal of Medicine2219-97642617-89822019-10-01171Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -IraqKamaran Mahmud SaidokaSalam Naser ZanganaRebaz Tahir Lak Background:Bronchial asthma is a common chronic respiratory disease worldwide. Although magnesium (Mg) deficiency has been shown to play a role in exacerbation of asthma, the exact prevalence of hypomagnesaemia in asthma is not clear. Objective: To estimate the serum Mg levels in bronchial asthma patients and compare them with healthy population and to evaluate the prevalence of hypomagnesaemia among them. Patients and Methods: A cross-sectional study was carried out in the respiratory unit of Rizgary Teaching Hospital involving 80 adult patients with chronic asthma (group I) and 80 healthy adult controls (group II). Serum magnesium level was measured in all the participants. Results: Hypomagnesaemia was detected in 20% of the asthmatic patients when compared to controls (0%) (p=0.001). No significant association was detected between magnesium status and type of asthma (p= 0.59). There was a statistically significant stage-wise decline in serum levels of Mg with increase in severity of asthma (p=0.02). Patients with severe asthma had the highest prevalence of hypomagnesaemia (45.5%) in comparison to mild and moderate cases (p=0.001). No significant associations were detected between the level of magnesium and the number of medications that the patients used, corticosteroids use, and theophylline therapy (p=0.06, 0.17, and 0.08, respectively). Hypomagnesaemia was significantly correlated with the duration of asthma (p=0.04). Conclusion: Hypomagnesaemia is more prevalent in chronic asthmatics than non-asthmatics. Hypomagnesaemia was significantly correlated with severity and duration of asthma. http://djm.uodiyala.edu.iq/index.php/djm/article/view/338Chronic asthma, Magnesium, Hypomagnesaemia
spellingShingle Kamaran Mahmud Saidoka
Salam Naser Zangana
Rebaz Tahir Lak
Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -Iraq
Diyala Journal of Medicine
Chronic asthma, Magnesium, Hypomagnesaemia
title Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -Iraq
title_full Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -Iraq
title_fullStr Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -Iraq
title_full_unstemmed Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -Iraq
title_short Estimation of Serum Magnesium level among Patients with Bronchial Asthma in Erbil -Iraq
title_sort estimation of serum magnesium level among patients with bronchial asthma in erbil iraq
topic Chronic asthma, Magnesium, Hypomagnesaemia
url http://djm.uodiyala.edu.iq/index.php/djm/article/view/338
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AT rebaztahirlak estimationofserummagnesiumlevelamongpatientswithbronchialasthmainerbiliraq