Hypotensive efficacy and cerebroprotective action of beta blocker metoprolol
The aim of the study was to investigate hypotensive and cerebroprotective activity ofmetoprolol inpatients with essential arterial hypertension (EAR). In all participants, 24-hour blood pressure (BP) monitoring, cerebral perfusion scintigraphy, and cognitive function assessment were performed at bas...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2005-02-01
|
| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/2495 |
| _version_ | 1826561643938578432 |
|---|---|
| author | N. L. Afanasyeva V. F. Mordovin N. Yu. Efimova G. V. Semke I. Yu. Efimova |
| author_facet | N. L. Afanasyeva V. F. Mordovin N. Yu. Efimova G. V. Semke I. Yu. Efimova |
| author_sort | N. L. Afanasyeva |
| collection | DOAJ |
| description | The aim of the study was to investigate hypotensive and cerebroprotective activity ofmetoprolol inpatients with essential arterial hypertension (EAR). In all participants, 24-hour blood pressure (BP) monitoring, cerebral perfusion scintigraphy, and cognitive function assessment were performed at baseline and after 6 weeks of treatment. After 6 weeks of therapy, according to 24-hour BP monitoring results, systolic and diastolic BP significantly declined. Cerebral blood flow substantially improved in parietal, frontal, and temporal areas. Cognitive function (memory, attention, thinking) also improved. Metoprolol optimally decreased BP and demonstrated cerebroprotective efficacy. |
| first_indexed | 2024-04-09T20:54:49Z |
| format | Article |
| id | doaj.art-e6bd90fdbff7483bb53af9d07014f461 |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2025-03-14T09:35:27Z |
| publishDate | 2005-02-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-e6bd90fdbff7483bb53af9d07014f4612025-03-02T11:42:20Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202005-02-010160642223Hypotensive efficacy and cerebroprotective action of beta blocker metoprololN. L. Afanasyeva0V. F. Mordovin1N. Yu. Efimova2G. V. Semke3I. Yu. Efimova4НИИ кардиологии ТНЦ СО РАМННИИ кардиологии ТНЦ СО РАМННИИ кардиологии ТНЦ СО РАМННИИ кардиологии ТНЦ СО РАМННИИ кардиологии ТНЦ СО РАМНThe aim of the study was to investigate hypotensive and cerebroprotective activity ofmetoprolol inpatients with essential arterial hypertension (EAR). In all participants, 24-hour blood pressure (BP) monitoring, cerebral perfusion scintigraphy, and cognitive function assessment were performed at baseline and after 6 weeks of treatment. After 6 weeks of therapy, according to 24-hour BP monitoring results, systolic and diastolic BP significantly declined. Cerebral blood flow substantially improved in parietal, frontal, and temporal areas. Cognitive function (memory, attention, thinking) also improved. Metoprolol optimally decreased BP and demonstrated cerebroprotective efficacy.https://russjcardiol.elpub.ru/jour/article/view/2495arterial hypertensionmetoprololcognitive function |
| spellingShingle | N. L. Afanasyeva V. F. Mordovin N. Yu. Efimova G. V. Semke I. Yu. Efimova Hypotensive efficacy and cerebroprotective action of beta blocker metoprolol Российский кардиологический журнал arterial hypertension metoprolol cognitive function |
| title | Hypotensive efficacy and cerebroprotective action of beta blocker metoprolol |
| title_full | Hypotensive efficacy and cerebroprotective action of beta blocker metoprolol |
| title_fullStr | Hypotensive efficacy and cerebroprotective action of beta blocker metoprolol |
| title_full_unstemmed | Hypotensive efficacy and cerebroprotective action of beta blocker metoprolol |
| title_short | Hypotensive efficacy and cerebroprotective action of beta blocker metoprolol |
| title_sort | hypotensive efficacy and cerebroprotective action of beta blocker metoprolol |
| topic | arterial hypertension metoprolol cognitive function |
| url | https://russjcardiol.elpub.ru/jour/article/view/2495 |
| work_keys_str_mv | AT nlafanasyeva hypotensiveefficacyandcerebroprotectiveactionofbetablockermetoprolol AT vfmordovin hypotensiveefficacyandcerebroprotectiveactionofbetablockermetoprolol AT nyuefimova hypotensiveefficacyandcerebroprotectiveactionofbetablockermetoprolol AT gvsemke hypotensiveefficacyandcerebroprotectiveactionofbetablockermetoprolol AT iyuefimova hypotensiveefficacyandcerebroprotectiveactionofbetablockermetoprolol |