Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysis
ObjectiveAlthough acupuncture is widely used as a complementary therapy in the treatment of Bell's palsy (BP) when to initiate acupuncture is still controversial. This study aims to determine the efficacy of the early intervention by acupuncture on BP.MethodsWe retrospectively gathered clinical...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2022.943453/full |
| _version_ | 1828104993034469376 |
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| author | Lian-Sheng Yang Lian-Sheng Yang Dan-Feng Zhou Shu-Zhen Zheng Bai-Ming Zhao Huo-Gui Li Qi-Qing Chen Yun Zhong Hong-Zhi Yang Kun Zhang Chun-Zhi Tang |
| author_facet | Lian-Sheng Yang Lian-Sheng Yang Dan-Feng Zhou Shu-Zhen Zheng Bai-Ming Zhao Huo-Gui Li Qi-Qing Chen Yun Zhong Hong-Zhi Yang Kun Zhang Chun-Zhi Tang |
| author_sort | Lian-Sheng Yang |
| collection | DOAJ |
| description | ObjectiveAlthough acupuncture is widely used as a complementary therapy in the treatment of Bell's palsy (BP) when to initiate acupuncture is still controversial. This study aims to determine the efficacy of the early intervention by acupuncture on BP.MethodsWe retrospectively gathered clinical data from the Third Affiliated Hospital of SUN-YAT SEN University between 2016 and 2021. We selected newly diagnosed patients with BP who were diagnosed by registered neurologists or acupuncturists formally. The qualified patients were divided into two groups according to whether or not initial acupuncture treatment was given within 7 days from the onset of palsy. Cohorts were balanced using 1:1 propensity score matching (PSM). Cox proportional hazards modeling and Kaplan–Meier analysis were applied to determine the differences between the two groups. The outcome included time to complete recovery of facial function, the rate of complete recovery, and the occurrence of sequelae in 24 weeks.ResultsA total of 345 patients were eligible for this study and were divided into the manual acupuncture/electroacupuncture (MA/EA) group (n = 76) and the EA group (n = 125). In the propensity score-matched cohort, the time to complete recovery was significantly shorter in the MA/EA group compared with the patients in the EA group (hazard ratio 1.505, 95% CI 1.028–2.404, p <0.05). The MA/EA group had a higher rate of favorable outcomes at 12 weeks than the EA group (93.4 vs. 80.3%, p = 0.032), and the occurrence of sequelae at 24 weeks showed a greater reducing trend in the MA/EA group than the EA group (6.6 vs. 16.4%, p = 0.088).ConclusionAcupuncture intervention at the acute stage of BP could shorten the time to recovery and improve the outcome.Clinical trial registrationhttp://www.chictr.org.cn, identifier ChiCTR 2200058060. |
| first_indexed | 2024-04-11T09:55:37Z |
| format | Article |
| id | doaj.art-e6be8f6ac92e47f382e03eac47048ba2 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-11T09:55:37Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-e6be8f6ac92e47f382e03eac47048ba22022-12-22T04:30:37ZengFrontiers Media S.A.Frontiers in Neurology1664-22952022-09-011310.3389/fneur.2022.943453943453Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysisLian-Sheng Yang0Lian-Sheng Yang1Dan-Feng Zhou2Shu-Zhen Zheng3Bai-Ming Zhao4Huo-Gui Li5Qi-Qing Chen6Yun Zhong7Hong-Zhi Yang8Kun Zhang9Chun-Zhi Tang10Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Traditional Chinese Medicine, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaDepartment of Acupuncture and Moxibustion, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, ChinaSouth China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, ChinaObjectiveAlthough acupuncture is widely used as a complementary therapy in the treatment of Bell's palsy (BP) when to initiate acupuncture is still controversial. This study aims to determine the efficacy of the early intervention by acupuncture on BP.MethodsWe retrospectively gathered clinical data from the Third Affiliated Hospital of SUN-YAT SEN University between 2016 and 2021. We selected newly diagnosed patients with BP who were diagnosed by registered neurologists or acupuncturists formally. The qualified patients were divided into two groups according to whether or not initial acupuncture treatment was given within 7 days from the onset of palsy. Cohorts were balanced using 1:1 propensity score matching (PSM). Cox proportional hazards modeling and Kaplan–Meier analysis were applied to determine the differences between the two groups. The outcome included time to complete recovery of facial function, the rate of complete recovery, and the occurrence of sequelae in 24 weeks.ResultsA total of 345 patients were eligible for this study and were divided into the manual acupuncture/electroacupuncture (MA/EA) group (n = 76) and the EA group (n = 125). In the propensity score-matched cohort, the time to complete recovery was significantly shorter in the MA/EA group compared with the patients in the EA group (hazard ratio 1.505, 95% CI 1.028–2.404, p <0.05). The MA/EA group had a higher rate of favorable outcomes at 12 weeks than the EA group (93.4 vs. 80.3%, p = 0.032), and the occurrence of sequelae at 24 weeks showed a greater reducing trend in the MA/EA group than the EA group (6.6 vs. 16.4%, p = 0.088).ConclusionAcupuncture intervention at the acute stage of BP could shorten the time to recovery and improve the outcome.Clinical trial registrationhttp://www.chictr.org.cn, identifier ChiCTR 2200058060.https://www.frontiersin.org/articles/10.3389/fneur.2022.943453/fullacupunctureBell's palsyreal world studypropensity score matchingretrospective study |
| spellingShingle | Lian-Sheng Yang Lian-Sheng Yang Dan-Feng Zhou Shu-Zhen Zheng Bai-Ming Zhao Huo-Gui Li Qi-Qing Chen Yun Zhong Hong-Zhi Yang Kun Zhang Chun-Zhi Tang Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysis Frontiers in Neurology acupuncture Bell's palsy real world study propensity score matching retrospective study |
| title | Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysis |
| title_full | Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysis |
| title_fullStr | Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysis |
| title_full_unstemmed | Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysis |
| title_short | Early intervention with acupuncture improves the outcome of patients with Bell's palsy: A propensity score-matching analysis |
| title_sort | early intervention with acupuncture improves the outcome of patients with bell s palsy a propensity score matching analysis |
| topic | acupuncture Bell's palsy real world study propensity score matching retrospective study |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2022.943453/full |
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