HMGXB4 Targets <i>Sleeping Beauty</i> Transposition to Germinal Stem Cells

HMGXB4 Targets <i>Sleeping Beauty</i> Transposition to Germinal Stem Cells

Transposons are parasitic genetic elements that frequently hijack vital cellular processes of their host. HMGXB4 is a known Wnt signaling-regulating HMG-box protein, previously identified as a host-encoded factor of <i>Sleeping Beauty</i> (SB) transposition. Here, we show that HMGXB4 is...

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Bibliographic Details
Main Authors: Anantharam Devaraj, Manvendra Singh, Suneel A Narayanavari, Guo Yong, Jiaxuan Chen, Jichang Wang, Mareike Becker, Oliver Walisko, Andrea Schorn, Zoltán Cseresznyés, Tamás Raskó, Kathrin Radscheit, Matthias Selbach, Zoltán Ivics, Zsuzsanna Izsvák
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Sleeping Beauty</i>
transposon
HMGXB4
transcriptional activator
H3K4me3
NuRF
Online Access:https://www.mdpi.com/1422-0067/24/8/7283

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