Investigating the potential of a prematurely aged immune phenotype in severely injured patients as predictor of risk of sepsis

Abstract Background Traumatic injury elicits a hyperinflammatory response and remodelling of the immune system leading to immuneparesis. This study aimed to evaluate whether traumatic injury results in a state of prematurely aged immune phenotype to relate this to clinical outcomes and a greater ris...

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Bibliographic Details
Main Authors: Mark A. Foster, Conor Bentley, Jon Hazeldine, Animesh Acharjee, Ornit Nahman, Shai S. Shen-Orr, Janet M. Lord, Niharika A. Duggal
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-022-00317-5