Investigating the potential of a prematurely aged immune phenotype in severely injured patients as predictor of risk of sepsis
Abstract Background Traumatic injury elicits a hyperinflammatory response and remodelling of the immune system leading to immuneparesis. This study aimed to evaluate whether traumatic injury results in a state of prematurely aged immune phenotype to relate this to clinical outcomes and a greater ris...
Main Authors: | Mark A. Foster, Conor Bentley, Jon Hazeldine, Animesh Acharjee, Ornit Nahman, Shai S. Shen-Orr, Janet M. Lord, Niharika A. Duggal |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-12-01
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Series: | Immunity & Ageing |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12979-022-00317-5 |
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