Lipid Aldehydes 4-Hydroxynonenal and 4-Hydroxyhexenal Exposure Differentially Impact Lipogenic Pathways in Human Placenta

Lipid Aldehydes 4-Hydroxynonenal and 4-Hydroxyhexenal Exposure Differentially Impact Lipogenic Pathways in Human Placenta

Long chain polyunsaturated fatty acids (LCPUFAs), such as the omega-6 (n-6) arachidonic acid (AA) and n-3 docosahexanoic acid (DHA), have a vital role in normal fetal development and placental function. Optimal supply of these LCPUFAs to the fetus is critical for improving birth outcomes and prevent...

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Bibliographic Details
Main Authors: Aisha Rasool, Taysir Mahmoud, Perrie O’Tierney-Ginn
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Biology
Subjects:
placenta
lipid aldehydes
4-HHE
4-HNE
fatty acid
Online Access:https://www.mdpi.com/2079-7737/12/4/527

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