Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction
OBJECTIVES: Acute ST-elevation myocardial infarction is associated with ventricular dysfunction due to ischemia-induced progressive myocardial damage. The decrease in ventricular compliance causes left atrial dilatation and stretching of the atrial myocardium, which are the main stimuli for the secr...
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| Format: | Article |
| Language: | English |
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Elsevier España
2013-07-01
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| Series: | Clinics |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000700997&lng=en&tlng=en |
| _version_ | 1811317165622558720 |
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| author | Ahmet Bacaksiz Mehmet Akif Vatankulu Mehmet Kayrak Hasan Huseyin Telli Selim S. Ayhan Osman Sonmez Ayse Alp Sadik Buyukbas |
| author_facet | Ahmet Bacaksiz Mehmet Akif Vatankulu Mehmet Kayrak Hasan Huseyin Telli Selim S. Ayhan Osman Sonmez Ayse Alp Sadik Buyukbas |
| author_sort | Ahmet Bacaksiz |
| collection | DOAJ |
| description | OBJECTIVES: Acute ST-elevation myocardial infarction is associated with ventricular dysfunction due to ischemia-induced progressive myocardial damage. The decrease in ventricular compliance causes left atrial dilatation and stretching of the atrial myocardium, which are the main stimuli for the secretion of atrial natriuretic peptide. The aim of this study was to evaluate left atrial dimensions and atrial natriuretic peptide levels in patients early after their first acute ST-elevation myocardial infarction and assess the probable interaction between coronary lesions and these measurements. METHODS: A total of 110 patients with acute myocardial infarction and 50 controls were studied. Plasma atrial natriuretic peptide was measured at admission. Left ventricular function, diameter, and volume index were evaluated using transthoracic echocardiography. Gensini and vessel scores of the patients who underwent coronary angiography were calculated. RESULTS: Plasma atrial natriuretic peptide in the patients with myocardial infarction was increased compared with that in controls (3.90±3.75 vs. 1.35±0.72 nmol/L, p<0.001). Although the left atrial diameter was comparable in patients and controls, the left atrial volume index was increased in patients with acute myocardial infarction (26.5±7.1 vs. 21.3±4.9 mL/m2, p<0.01). Multivariate regression analysis showed a strong independent correlation between the left atrial volume index and the plasma atrial natriuretic peptide level (β = 0.23, p = 0.03). CONCLUSIONS: The left atrial volume index and plasma atrial natriuretic peptide level were correlated in patients with acute myocardial infarction. |
| first_indexed | 2024-04-13T12:03:19Z |
| format | Article |
| id | doaj.art-e6d4a9e3c97b4cf29ac57cf9f774db4e |
| institution | Directory Open Access Journal |
| issn | 1980-5322 |
| language | English |
| last_indexed | 2024-04-13T12:03:19Z |
| publishDate | 2013-07-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-e6d4a9e3c97b4cf29ac57cf9f774db4e2022-12-22T02:47:44ZengElsevier EspañaClinics1980-53222013-07-01687997100310.6061/clinics/2013(07)18S1807-59322013000700997Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarctionAhmet BacaksizMehmet Akif VatankuluMehmet KayrakHasan Huseyin TelliSelim S. AyhanOsman SonmezAyse AlpSadik BuyukbasOBJECTIVES: Acute ST-elevation myocardial infarction is associated with ventricular dysfunction due to ischemia-induced progressive myocardial damage. The decrease in ventricular compliance causes left atrial dilatation and stretching of the atrial myocardium, which are the main stimuli for the secretion of atrial natriuretic peptide. The aim of this study was to evaluate left atrial dimensions and atrial natriuretic peptide levels in patients early after their first acute ST-elevation myocardial infarction and assess the probable interaction between coronary lesions and these measurements. METHODS: A total of 110 patients with acute myocardial infarction and 50 controls were studied. Plasma atrial natriuretic peptide was measured at admission. Left ventricular function, diameter, and volume index were evaluated using transthoracic echocardiography. Gensini and vessel scores of the patients who underwent coronary angiography were calculated. RESULTS: Plasma atrial natriuretic peptide in the patients with myocardial infarction was increased compared with that in controls (3.90±3.75 vs. 1.35±0.72 nmol/L, p<0.001). Although the left atrial diameter was comparable in patients and controls, the left atrial volume index was increased in patients with acute myocardial infarction (26.5±7.1 vs. 21.3±4.9 mL/m2, p<0.01). Multivariate regression analysis showed a strong independent correlation between the left atrial volume index and the plasma atrial natriuretic peptide level (β = 0.23, p = 0.03). CONCLUSIONS: The left atrial volume index and plasma atrial natriuretic peptide level were correlated in patients with acute myocardial infarction.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000700997&lng=en&tlng=enMyocardial InfarctionAtrial Natriuretic PeptideHeart Atria |
| spellingShingle | Ahmet Bacaksiz Mehmet Akif Vatankulu Mehmet Kayrak Hasan Huseyin Telli Selim S. Ayhan Osman Sonmez Ayse Alp Sadik Buyukbas Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction Clinics Myocardial Infarction Atrial Natriuretic Peptide Heart Atria |
| title | Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction |
| title_full | Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction |
| title_fullStr | Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction |
| title_full_unstemmed | Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction |
| title_short | Assessment of the left atrial volume index and plasma NT-proANP level in patients with acute ST-elevation myocardial infarction |
| title_sort | assessment of the left atrial volume index and plasma nt proanp level in patients with acute st elevation myocardial infarction |
| topic | Myocardial Infarction Atrial Natriuretic Peptide Heart Atria |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322013000700997&lng=en&tlng=en |
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