Fully Symmetric Cyclodextrin Polycarboxylates: How to Determine Reliable Protonation Constants from NMR Titration Data

Fully Symmetric Cyclodextrin Polycarboxylates: How to Determine Reliable Protonation Constants from NMR Titration Data

Acid-base properties of cyclodextrins (CDs), persubstituted at C-6 by 3-mercaptopropionic acid, sualphadex (Suα-CD), subetadex (Suβ-CD) and sugammadex (Suγ-CD, the antidote of neuromuscular blocking steroids) were studied by <sup>1</sup>H NMR-pH titrations. For each CD, the severe overla...

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Bibliographic Details
Main Authors:	Eszter Kalydi, Milo Malanga, Dóra Ujj, Gábor Benkovics, Zoltán Szakács, Szabolcs Béni
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	International Journal of Molecular Sciences
Subjects:	cyclodextrins sugammadex <sup>1</sup>H NMR pH-titration protonation microconstant cluster expansion model parameter correlation
Online Access:	https://www.mdpi.com/1422-0067/23/22/14448

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