Nitrate Reductase NarGHJI Modulates Virulence via Regulation of agr Expression in Methicillin-Resistant Staphylococcus aureus Strain USA300 LAC

Nitrate Reductase NarGHJI Modulates Virulence via Regulation of agr Expression in Methicillin-Resistant Staphylococcus aureus Strain USA300 LAC

ABSTRACT Staphylococcus aureus is a pathogenic bacterium with a widespread distribution that can cause diverse severe diseases. The membrane-bound nitrate reductase NarGHJI serves respiratory function. However, little is known about its contribution to virulence. In this study, we demonstrated that...

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Bibliographic Details
Main Authors: Yujie Li, Ting Pan, Ruobing Cao, Wei Li, Zhien He, Baolin Sun
Format: Article
Language:English
Published: American Society for Microbiology 2023-06-01
Series:Microbiology Spectrum
Subjects:
nitrate reductase
NarGHJI
Staphylococcus aureus
agr system
cytokine
alpha-hemolysin
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03596-22

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