Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria

The prevalence and sensitivity pattern of urinary pathogens from 1240 patients in Port-harcourt, Nigeria was investigated. The predominant pathogens cultured was E. coli which accounted for 76.6% of the infections. Klebsiella spp was responsible for 8.1% of cases while the rest were accounted for by...

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Main Authors: JC Uwaezuoke, JN Ogbulie
Format: Article
Language:English
Published: Joint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP) 2006-10-01
Series:Journal of Applied Sciences and Environmental Management
Online Access:https://www.ajol.info/index.php/jasem/article/view/17328
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author JC Uwaezuoke
JN Ogbulie
author_facet JC Uwaezuoke
JN Ogbulie
author_sort JC Uwaezuoke
collection DOAJ
description The prevalence and sensitivity pattern of urinary pathogens from 1240 patients in Port-harcourt, Nigeria was investigated. The predominant pathogens cultured was E. coli which accounted for 76.6% of the infections. Klebsiella spp was responsible for 8.1% of cases while the rest were accounted for by Proteus spp (4.8%), coagulase-negative staphylococci (3.2%), Pseudomonas spp (2.4%), Enterobacter spp. (2.4%), Staphylococcus aureus (1.6%) and Citrobacter species (0.8%). The majority of the isolates were resistant to tetracycline (75.8%), ampicillin (71.0%) and cotrimoxazole (65.3%) but exhibited good sensitivity to nitrofurantoin (88.7%), gentamicin (85.5%) and nalidixic acid (76.6%). It is recommended that a periodic reassessment of the sensitivity pattern of urinary pathogens be carried out to serve as a guide for antibiotic therapy of UTIs in a particular environment since these organisms exhibited resistance to first-line drugs used for UTI infections. Journal of Applied Sciences and Environmental Management Vol. 10(3) 2006: 103-107
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spelling doaj.art-e6d9106b9624498b809c8d984dd1991c2024-04-02T19:54:34ZengJoint Coordination Centre of the World Bank assisted National Agricultural Research Programme (NARP)Journal of Applied Sciences and Environmental Management2659-15022659-14992006-10-0110310.4314/jasem.v10i3.17328Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, NigeriaJC Uwaezuoke0JN Ogbulie1Imo State University P.M.B. 2000, Owerri, NigeriaFederal University of Technology, Owerri, NigeriaThe prevalence and sensitivity pattern of urinary pathogens from 1240 patients in Port-harcourt, Nigeria was investigated. The predominant pathogens cultured was E. coli which accounted for 76.6% of the infections. Klebsiella spp was responsible for 8.1% of cases while the rest were accounted for by Proteus spp (4.8%), coagulase-negative staphylococci (3.2%), Pseudomonas spp (2.4%), Enterobacter spp. (2.4%), Staphylococcus aureus (1.6%) and Citrobacter species (0.8%). The majority of the isolates were resistant to tetracycline (75.8%), ampicillin (71.0%) and cotrimoxazole (65.3%) but exhibited good sensitivity to nitrofurantoin (88.7%), gentamicin (85.5%) and nalidixic acid (76.6%). It is recommended that a periodic reassessment of the sensitivity pattern of urinary pathogens be carried out to serve as a guide for antibiotic therapy of UTIs in a particular environment since these organisms exhibited resistance to first-line drugs used for UTI infections. Journal of Applied Sciences and Environmental Management Vol. 10(3) 2006: 103-107https://www.ajol.info/index.php/jasem/article/view/17328
spellingShingle JC Uwaezuoke
JN Ogbulie
Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria
Journal of Applied Sciences and Environmental Management
title Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria
title_full Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria
title_fullStr Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria
title_full_unstemmed Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria
title_short Antibiotic sensitivity pattern of urinary tract pathogens in Port – Harcourt, Nigeria
title_sort antibiotic sensitivity pattern of urinary tract pathogens in port harcourt nigeria
url https://www.ajol.info/index.php/jasem/article/view/17328
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