Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension

Background: To assess the impact of our surgical strategy for the treatment of patients with functional single ventricle and pulmonary hypertension, especially in patients>24 months old. Methods We retrospectively analyzed the clinical data of 97 patients with functional single ventricle and pulm...

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Main Authors: Gang Li, Han Zhang, Xiangming Fan, Junwu Su
Format: Article
Language:English
Published: Taylor & Francis Group 2021-05-01
Series:Clinical and Experimental Hypertension
Subjects:
Online Access:http://dx.doi.org/10.1080/10641963.2021.1883048
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author Gang Li
Han Zhang
Xiangming Fan
Junwu Su
author_facet Gang Li
Han Zhang
Xiangming Fan
Junwu Su
author_sort Gang Li
collection DOAJ
description Background: To assess the impact of our surgical strategy for the treatment of patients with functional single ventricle and pulmonary hypertension, especially in patients>24 months old. Methods We retrospectively analyzed the clinical data of 97 patients with functional single ventricle and pulmonary hypertension undergoing pulmonary artery banding (PAB) in our hospital between April 2010 and December 2018. The surgical results, transition to Glenn operation and subsequent transition to Fontan operation were analyzed. Results: The 97 patients underwent PAB included 34 patients>24 months old, hospital mortality was 2.1% (2/97). 62 patients underwent the second-stage Glenn operation, and 21 patients underwent third-stage Fontan operation. On competing risk analysis, at 80 months after PAB, 81% had undergone the Glenn operation, and 13% were awaiting the Glenn operation. At 35 months after the Glenn operation, 2% of patients had died, 63% had undergone the Fontan operation, and 36% were awaiting the Fontan operation. Conclusion: PAB is an acceptable strategy for patients with functional single ventricle associated with pulmonary hypertension. Outcomes and results of subsequent Glenn and Fontan procedures are generally good included patients>24 months. Accompanied with unbalanced atrioventricular septal defect for lower ratio of transition to Glenn and Fontan operation.
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spelling doaj.art-e6dc81f2f093492196030adb92df0e362023-09-19T15:19:29ZengTaylor & Francis GroupClinical and Experimental Hypertension1064-19631525-60062021-05-0143432833310.1080/10641963.2021.18830481883048Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertensionGang Li0Han Zhang1Xiangming Fan2Junwu Su3Capital Medical University, Beijing Institute of Heart Lung and Blood Vessel DiseasesCapital Medical University, Beijing Institute of Heart Lung and Blood Vessel DiseasesCapital Medical University, Beijing Institute of Heart Lung and Blood Vessel DiseasesCapital Medical University, Beijing Institute of Heart Lung and Blood Vessel DiseasesBackground: To assess the impact of our surgical strategy for the treatment of patients with functional single ventricle and pulmonary hypertension, especially in patients>24 months old. Methods We retrospectively analyzed the clinical data of 97 patients with functional single ventricle and pulmonary hypertension undergoing pulmonary artery banding (PAB) in our hospital between April 2010 and December 2018. The surgical results, transition to Glenn operation and subsequent transition to Fontan operation were analyzed. Results: The 97 patients underwent PAB included 34 patients>24 months old, hospital mortality was 2.1% (2/97). 62 patients underwent the second-stage Glenn operation, and 21 patients underwent third-stage Fontan operation. On competing risk analysis, at 80 months after PAB, 81% had undergone the Glenn operation, and 13% were awaiting the Glenn operation. At 35 months after the Glenn operation, 2% of patients had died, 63% had undergone the Fontan operation, and 36% were awaiting the Fontan operation. Conclusion: PAB is an acceptable strategy for patients with functional single ventricle associated with pulmonary hypertension. Outcomes and results of subsequent Glenn and Fontan procedures are generally good included patients>24 months. Accompanied with unbalanced atrioventricular septal defect for lower ratio of transition to Glenn and Fontan operation.http://dx.doi.org/10.1080/10641963.2021.1883048functional single ventriclepulmonary hypertensionpulmonary artery bandingstaged operations
spellingShingle Gang Li
Han Zhang
Xiangming Fan
Junwu Su
Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension
Clinical and Experimental Hypertension
functional single ventricle
pulmonary hypertension
pulmonary artery banding
staged operations
title Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension
title_full Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension
title_fullStr Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension
title_full_unstemmed Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension
title_short Pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension
title_sort pulmonary artery banding in patients with functional single ventricle associated with pulmonary hypertension
topic functional single ventricle
pulmonary hypertension
pulmonary artery banding
staged operations
url http://dx.doi.org/10.1080/10641963.2021.1883048
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