Multi-label transcriptional classification of colorectal cancer reflects tumor cell population heterogeneity

Abstract Background Transcriptional classification has been used to stratify colorectal cancer (CRC) into molecular subtypes with distinct biological and clinical features. However, it is not clear whether such subtypes represent discrete, mutually exclusive entities or molecular/phenotypic states w...

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Détails bibliographiques
Auteurs principaux: Silvia Cascianelli, Chiara Barbera, Alexandra Ambra Ulla, Elena Grassi, Barbara Lupo, Diego Pasini, Andrea Bertotti, Livio Trusolino, Enzo Medico, Claudio Isella, Marco Masseroli
Format: Article
Langue:English
Publié: BMC 2023-05-01
Collection:Genome Medicine
Sujets:
Accès en ligne:https://doi.org/10.1186/s13073-023-01176-5