Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by Shock
Objective: to evaluate the efficiency of the elaborated intensive therapy policy for acute acetic acid poisoning complicated by exotoxic shock.Subjects and methods. The results of treatment were analyzed in 72 patients admitted in 2008—2012 with severe acute acetic acid poisoning complicated by exot...
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| Format: | Article |
| Language: | English |
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Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2014-06-01
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| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1336 |
| _version_ | 1826562268794454016 |
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| author | A. A. Stopnitsky R. N. Akalaev |
| author_facet | A. A. Stopnitsky R. N. Akalaev |
| author_sort | A. A. Stopnitsky |
| collection | DOAJ |
| description | Objective: to evaluate the efficiency of the elaborated intensive therapy policy for acute acetic acid poisoning complicated by exotoxic shock.Subjects and methods. The results of treatment were analyzed in 72 patients admitted in 2008—2012 with severe acute acetic acid poisoning complicated by exotoxic shock. The patients were divided into 2 groups: 1) combination therapy added by an improved intensive therapy complex; 2) conventional therapy. All the patients underwent comprehensive clinical and laboratory examination.Results and discussion. Group 1 versus the study group showed 1.7-, 2.0-, and 2.4- fold increases in the reduction of free hemoglobin levels 12, 24, and 48 hours after applying the improved complex of intensive therapy, respectively. In Group 1, hemodynamic and acidbase balance parameters recovered much faster and the incidence of acute renal failure and mortality rates were 2.1 and 2.0 times lower than those in the comparison group.Conclusion. Incorporation of the agents that correct volemic disorders and improve microcirculation into intensive therapy for acute acetic acid poisoning can considerably reduce the time of shock emergence, prevent acute renal failure, and decrease mortality rates. |
| first_indexed | 2024-04-10T01:28:48Z |
| format | Article |
| id | doaj.art-e6e9177f3ba34f5fa8d8ee8ddd961e23 |
| institution | Directory Open Access Journal |
| issn | 1813-9779 2411-7110 |
| language | English |
| last_indexed | 2025-03-14T09:45:23Z |
| publishDate | 2014-06-01 |
| publisher | Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia |
| record_format | Article |
| series | Общая реаниматология |
| spelling | doaj.art-e6e9177f3ba34f5fa8d8ee8ddd961e232025-03-02T11:29:33ZengFederal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, RussiaОбщая реаниматология1813-97792411-71102014-06-01102182210.15360/1813-9779-2014-2-18-221336Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by ShockA. A. Stopnitsky0R. N. Akalaev1Republican Research Center for Emergency Medical Care, Tashkent, Republic of Uzbekistan Tashkent Institute for Postgraduate Training of Physicians, Republic of UzbekistanRepublican Research Center for Emergency Medical Care, Tashkent, Republic of Uzbekistan Tashkent Institute for Postgraduate Training of Physicians, Republic of UzbekistanObjective: to evaluate the efficiency of the elaborated intensive therapy policy for acute acetic acid poisoning complicated by exotoxic shock.Subjects and methods. The results of treatment were analyzed in 72 patients admitted in 2008—2012 with severe acute acetic acid poisoning complicated by exotoxic shock. The patients were divided into 2 groups: 1) combination therapy added by an improved intensive therapy complex; 2) conventional therapy. All the patients underwent comprehensive clinical and laboratory examination.Results and discussion. Group 1 versus the study group showed 1.7-, 2.0-, and 2.4- fold increases in the reduction of free hemoglobin levels 12, 24, and 48 hours after applying the improved complex of intensive therapy, respectively. In Group 1, hemodynamic and acidbase balance parameters recovered much faster and the incidence of acute renal failure and mortality rates were 2.1 and 2.0 times lower than those in the comparison group.Conclusion. Incorporation of the agents that correct volemic disorders and improve microcirculation into intensive therapy for acute acetic acid poisoning can considerably reduce the time of shock emergence, prevent acute renal failure, and decrease mortality rates.https://www.reanimatology.com/rmt/article/view/1336acetic acid, exotoxic shock, combination therapy, 6% hydroxyethyl starch solution, rheosorbilact, succinic acid, hemodynamic parameters, acid-base balance |
| spellingShingle | A. A. Stopnitsky R. N. Akalaev Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by Shock Общая реаниматология acetic acid, exotoxic shock, combination therapy, 6% hydroxyethyl starch solution, rheosorbilact, succinic acid, hemodynamic parameters, acid-base balance |
| title | Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by Shock |
| title_full | Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by Shock |
| title_fullStr | Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by Shock |
| title_full_unstemmed | Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by Shock |
| title_short | Intensive Therapy of Patients with Acetic Acid Poisoning Complicated by Shock |
| title_sort | intensive therapy of patients with acetic acid poisoning complicated by shock |
| topic | acetic acid, exotoxic shock, combination therapy, 6% hydroxyethyl starch solution, rheosorbilact, succinic acid, hemodynamic parameters, acid-base balance |
| url | https://www.reanimatology.com/rmt/article/view/1336 |
| work_keys_str_mv | AT aastopnitsky intensivetherapyofpatientswithaceticacidpoisoningcomplicatedbyshock AT rnakalaev intensivetherapyofpatientswithaceticacidpoisoningcomplicatedbyshock |