Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patients

Aims: The atrioventricular block (AVB) is a conduction system problem that results from the impairment in the transmission of an impulse from the atria to the ventricle, the disease has many etiologies. This article aimed to evaluate the efficacy and safety of dual and single-chamber pacemakers in p...

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Main Authors: Abdul Rehman Shah Syed, Abdullah Akram, Muhammad Shaheryar Azam, Ayesha Irshad Ansari, Muhammad Ali Muzammil, Abdul Ahad Syed, Shaheer Ahmed, Syeda Javeria Zakir
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023110851
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author Abdul Rehman Shah Syed
Abdullah Akram
Muhammad Shaheryar Azam
Ayesha Irshad Ansari
Muhammad Ali Muzammil
Abdul Ahad Syed
Shaheer Ahmed
Syeda Javeria Zakir
author_facet Abdul Rehman Shah Syed
Abdullah Akram
Muhammad Shaheryar Azam
Ayesha Irshad Ansari
Muhammad Ali Muzammil
Abdul Ahad Syed
Shaheer Ahmed
Syeda Javeria Zakir
author_sort Abdul Rehman Shah Syed
collection DOAJ
description Aims: The atrioventricular block (AVB) is a conduction system problem that results from the impairment in the transmission of an impulse from the atria to the ventricle, the disease has many etiologies. This article aimed to evaluate the efficacy and safety of dual and single-chamber pacemakers in patients with SSS and AVB. Methods: An electronic search of PubMed (Medline), EMBASE, and Google Scholar was performed from 2000 till August 15th, 2022. Retrieved articles were exported to Endnote Reference Library Software, where duplicate studies were removed from the list, and only articles meeting the eligibility criteria of this study were selected. RevMan 5.4 and STATA 16 software were used for the analysis. The modified Cochrane Collaboration's risk of bias and New-castle Ottawa scale were used for quality assessment of RCTs and observational studies respectively. Results: This study is composed of 8953 patients with sick-sinus syndrome and atrioventricular block. A total of thirteen outcomes are included in this meta-analysis, out of which atrial fibrillation significantly favored dual chamber [OR = 1.29; 95 % CI = 1.05–1.59; P = 0.01 I2 = 29 %] and overall complications [OR = 0.48; 95 % CI = 0.29–0.77; p = 0.03 I2 = 0 %] and pneumothorax [OR = 0.31; 95 % CI = 0.10–0.93; p = 0.04, I2 = 0 %] were satisfied by single-chamber pacing. Conclusion: This study concluded that neither single-chamber nor dual-chamber pacemakers are superior to each other, but they are unique in their own ways as the results of this study manifest remarkable reduction in atrial fibrillation rates and pneumothorax using dual-chamber and single-chamber pacemakers respectively.
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spelling doaj.art-e6e9ff394f89469cb75d89e36cb015482024-02-01T06:33:57ZengElsevierHeliyon2405-84402024-01-01101e23877Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patientsAbdul Rehman Shah Syed0Abdullah Akram1Muhammad Shaheryar Azam2Ayesha Irshad Ansari3Muhammad Ali Muzammil4Abdul Ahad Syed5Shaheer Ahmed6Syeda Javeria Zakir7Corresponding author.; Dow University of Health Science (Medicine), PakistanDow University of Health Science (Medicine), PakistanDow University of Health Science (Medicine), PakistanDow University of Health Science (Medicine), PakistanDow University of Health Science (Medicine), PakistanDow University of Health Science (Medicine), PakistanDow University of Health Science (Medicine), PakistanDow University of Health Science (Medicine), PakistanAims: The atrioventricular block (AVB) is a conduction system problem that results from the impairment in the transmission of an impulse from the atria to the ventricle, the disease has many etiologies. This article aimed to evaluate the efficacy and safety of dual and single-chamber pacemakers in patients with SSS and AVB. Methods: An electronic search of PubMed (Medline), EMBASE, and Google Scholar was performed from 2000 till August 15th, 2022. Retrieved articles were exported to Endnote Reference Library Software, where duplicate studies were removed from the list, and only articles meeting the eligibility criteria of this study were selected. RevMan 5.4 and STATA 16 software were used for the analysis. The modified Cochrane Collaboration's risk of bias and New-castle Ottawa scale were used for quality assessment of RCTs and observational studies respectively. Results: This study is composed of 8953 patients with sick-sinus syndrome and atrioventricular block. A total of thirteen outcomes are included in this meta-analysis, out of which atrial fibrillation significantly favored dual chamber [OR = 1.29; 95 % CI = 1.05–1.59; P = 0.01 I2 = 29 %] and overall complications [OR = 0.48; 95 % CI = 0.29–0.77; p = 0.03 I2 = 0 %] and pneumothorax [OR = 0.31; 95 % CI = 0.10–0.93; p = 0.04, I2 = 0 %] were satisfied by single-chamber pacing. Conclusion: This study concluded that neither single-chamber nor dual-chamber pacemakers are superior to each other, but they are unique in their own ways as the results of this study manifest remarkable reduction in atrial fibrillation rates and pneumothorax using dual-chamber and single-chamber pacemakers respectively.http://www.sciencedirect.com/science/article/pii/S2405844023110851Sick-sinus syndromeAtrioventricular blockpacemakeratrial fibrillationHeart failure care
spellingShingle Abdul Rehman Shah Syed
Abdullah Akram
Muhammad Shaheryar Azam
Ayesha Irshad Ansari
Muhammad Ali Muzammil
Abdul Ahad Syed
Shaheer Ahmed
Syeda Javeria Zakir
Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patients
Heliyon
Sick-sinus syndrome
Atrioventricular block
pacemaker
atrial fibrillation
Heart failure care
title Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patients
title_full Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patients
title_fullStr Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patients
title_full_unstemmed Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patients
title_short Dual-chamber versus single chamber pacemakers, a systemic review and meta-analysis on sick sinus syndrome and atrioventricular block patients
title_sort dual chamber versus single chamber pacemakers a systemic review and meta analysis on sick sinus syndrome and atrioventricular block patients
topic Sick-sinus syndrome
Atrioventricular block
pacemaker
atrial fibrillation
Heart failure care
url http://www.sciencedirect.com/science/article/pii/S2405844023110851
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