Regulation of MT1-MMP and MMP-2 by the Serpin PEDF: a Promising New Target for Metastatic Cancer

Regulation of MT1-MMP and MMP-2 by the Serpin PEDF: a Promising New Target for Metastatic Cancer

The balance of endogenous angiogenic factors in the body is responsible for the homeostatic control of angiogenesis during normal physiological circumstances, with the disruption of this fragile balance leading to pathologic angiogenic events such as those involved in cancer progression. This review...

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Bibliographic Details
Main Authors: Marice B. Alcantara, Crispin R. Dass
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2012-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Collagen
MMP-14
Cancer
PEDF
Metastasis
MT1-MMP
MMP-2
Online Access:http://www.karger.com/Article/FullText/350069

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