Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse

Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse

Epigenetic compounds have become attractive small molecules for targeting the multifaceted aspects of Alzheimer’s disease (AD). Although AD disproportionately affects women, most of the current literature investigating epigenetic compounds for the treatment of AD do not report sex-specific results....

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Bibliographic Details
Main Authors: Jessica Dennison, Armando Mendez, Angela Szeto, Ines Lohse, Claes Wahlestedt, Claude-Henry Volmar
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomolecules
Subjects:
Alzheimer’s
epigenetics
HDAC inhibitor
sex differences
3xTg-AD mouse
Online Access:https://www.mdpi.com/2218-273X/13/9/1324

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