The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition

Introduction: Gout is the most prevalent inflammatory crystal arthropathy worldwide and is a chronic disease requiring strict, lifelong adherence to drug therapy and healthy lifestyles. Gout has a heavy burden on the patient's sexual health, owing to the associated inflammatory status, long-ter...

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Main Authors: Andrea Sansone, Yacov Reisman, Suada Meto, Susanna Dolci, Emmanuele A. Jannini
Format: Article
Language:English
Published: Oxford University Press 2022-10-01
Series:Sexual Medicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2050116122000770
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author Andrea Sansone
Yacov Reisman
Suada Meto
Susanna Dolci
Emmanuele A. Jannini
author_facet Andrea Sansone
Yacov Reisman
Suada Meto
Susanna Dolci
Emmanuele A. Jannini
author_sort Andrea Sansone
collection DOAJ
description Introduction: Gout is the most prevalent inflammatory crystal arthropathy worldwide and is a chronic disease requiring strict, lifelong adherence to drug therapy and healthy lifestyles. Gout has a heavy burden on the patient's sexual health, owing to the associated inflammatory status, long-term complications, and chronic pain; however, the effects of gout also extend to the partner's sexual health. Aims: We aimed to investigate how the presence of a partner could influence the complex interaction between risk factors for sexual dysfunctions in gout in order to define novel strategies to improve sexual health and disease management. Methods: Clinical and experimental data on the role of the couple in chronic diseases, as well as on the association between gout and sexual health, were searched through Pubmed. Main outcome measures: Evidence from studies describing how the presence of a couple and leveraging sexual health can improve management and clinical outcomes for chronic diseases. Results: Treatment adherence can improve the sexual health of gout patients and their partners; likewise, by leveraging sexual health, it would be possible to promote better health-seeking behaviors, ultimately improving gout management. Clinical implications: Promoting awareness of the sexual health relevance of gout can potentially be a pivotal strategy to improve disease management and prevent the progression of sexual dysfunctions from subclinical to overt forms. Strengths and limitations: Identifying a bidirectional association between sexual health and disease management paves the way for improved disease control and can potentially prevent the development of sexual dysfunctions in couples affected by gout. However, the relevance of the couple has not been adequately addressed in gout management, and most evidence comes from other chronic diseases. Conclusion: Improving gout management results in better sexual health, and vice-versa promoting better sexual health can improve disease control for gout. The presence of a partner improves the behavioral well-being of gout patients, with beneficial effects on both sexual health and gout management.Sansone A, Reisman Y, Meto S, et al. The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition. Sex Med 2022;10:100562.
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spelling doaj.art-e6ecc4518b134f8287bbfbd3ef43e20c2023-08-02T07:33:01ZengOxford University PressSexual Medicine2050-11612022-10-01105100562The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With DepositionAndrea Sansone0Yacov Reisman1Suada Meto2Susanna Dolci3Emmanuele A. Jannini4Chair of Endocrinology & Medical Sexology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, ItalyFlare Health, Amstelveen, The NetherlandsA. Menarini Industrie Farmaceutiche Riunite S.R.L, Florence, ItalyChair of Anatomy, Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, ItalyChair of Endocrinology & Medical Sexology, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; Corresponding Author: Prof. Emmanuele A. Jannini, Chair of Endocrinology & Medical Sexology, Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier, 1, 00133 Rome, ItalyIntroduction: Gout is the most prevalent inflammatory crystal arthropathy worldwide and is a chronic disease requiring strict, lifelong adherence to drug therapy and healthy lifestyles. Gout has a heavy burden on the patient's sexual health, owing to the associated inflammatory status, long-term complications, and chronic pain; however, the effects of gout also extend to the partner's sexual health. Aims: We aimed to investigate how the presence of a partner could influence the complex interaction between risk factors for sexual dysfunctions in gout in order to define novel strategies to improve sexual health and disease management. Methods: Clinical and experimental data on the role of the couple in chronic diseases, as well as on the association between gout and sexual health, were searched through Pubmed. Main outcome measures: Evidence from studies describing how the presence of a couple and leveraging sexual health can improve management and clinical outcomes for chronic diseases. Results: Treatment adherence can improve the sexual health of gout patients and their partners; likewise, by leveraging sexual health, it would be possible to promote better health-seeking behaviors, ultimately improving gout management. Clinical implications: Promoting awareness of the sexual health relevance of gout can potentially be a pivotal strategy to improve disease management and prevent the progression of sexual dysfunctions from subclinical to overt forms. Strengths and limitations: Identifying a bidirectional association between sexual health and disease management paves the way for improved disease control and can potentially prevent the development of sexual dysfunctions in couples affected by gout. However, the relevance of the couple has not been adequately addressed in gout management, and most evidence comes from other chronic diseases. Conclusion: Improving gout management results in better sexual health, and vice-versa promoting better sexual health can improve disease control for gout. The presence of a partner improves the behavioral well-being of gout patients, with beneficial effects on both sexual health and gout management.Sansone A, Reisman Y, Meto S, et al. The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition. Sex Med 2022;10:100562.http://www.sciencedirect.com/science/article/pii/S2050116122000770
spellingShingle Andrea Sansone
Yacov Reisman
Suada Meto
Susanna Dolci
Emmanuele A. Jannini
The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition
Sexual Medicine
title The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition
title_full The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition
title_fullStr The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition
title_full_unstemmed The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition
title_short The Role of the “Anti-Inflammatory” Couple for the Management of Hyperuricemia With Deposition
title_sort role of the anti inflammatory couple for the management of hyperuricemia with deposition
url http://www.sciencedirect.com/science/article/pii/S2050116122000770
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