Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary Conditions

We focus on a quasi-one-dimensional Poisson–Nernst–Planck model with small permanent charges for ionic flows of two oppositely charged ion species through an ion channel. Of particular interest is to examine the dynamics of ionic flows in terms of I–V (current–voltage) relations with boundary layers...

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Main Authors: Yiwei Wang, Lijun Zhang, Mingji Zhang
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/13/2/131
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author Yiwei Wang
Lijun Zhang
Mingji Zhang
author_facet Yiwei Wang
Lijun Zhang
Mingji Zhang
author_sort Yiwei Wang
collection DOAJ
description We focus on a quasi-one-dimensional Poisson–Nernst–Planck model with small permanent charges for ionic flows of two oppositely charged ion species through an ion channel. Of particular interest is to examine the dynamics of ionic flows in terms of I–V (current–voltage) relations with boundary layers due to the relaxation of neutral conditions on boundary concentrations. This is achieved by employing the regular perturbation analysis on the solutions established through geometric singular perturbation analysis. Rich dynamics are observed, particularly, the nonlinear interplays among different physical parameters are characterized. Critical potentials are identified, which play critical roles in the study of ionic flows and can be estimated experimentally. Numerical simulations are performed to further illustrate and provide more intuitive understandings of our analytical results.
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spelling doaj.art-e6efc5e07c5e4326b6d3d9a814d497072023-11-16T22:01:47ZengMDPI AGMembranes2077-03752023-01-0113213110.3390/membranes13020131Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary ConditionsYiwei Wang0Lijun Zhang1Mingji Zhang2College of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao 266590, ChinaCollege of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao 266590, ChinaCollege of Mathematics and Systems Science, Shandong University of Science and Technology, Qingdao 266590, ChinaWe focus on a quasi-one-dimensional Poisson–Nernst–Planck model with small permanent charges for ionic flows of two oppositely charged ion species through an ion channel. Of particular interest is to examine the dynamics of ionic flows in terms of I–V (current–voltage) relations with boundary layers due to the relaxation of neutral conditions on boundary concentrations. This is achieved by employing the regular perturbation analysis on the solutions established through geometric singular perturbation analysis. Rich dynamics are observed, particularly, the nonlinear interplays among different physical parameters are characterized. Critical potentials are identified, which play critical roles in the study of ionic flows and can be estimated experimentally. Numerical simulations are performed to further illustrate and provide more intuitive understandings of our analytical results.https://www.mdpi.com/2077-0375/13/2/131PNPpermanent chargesI–V relationscritical potentialsboundary layers
spellingShingle Yiwei Wang
Lijun Zhang
Mingji Zhang
Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary Conditions
Membranes
PNP
permanent charges
I–V relations
critical potentials
boundary layers
title Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary Conditions
title_full Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary Conditions
title_fullStr Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary Conditions
title_full_unstemmed Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary Conditions
title_short Mathematical Analysis on Current–Voltage Relations via Classical Poisson–Nernst–Planck Systems with Nonzero Permanent Charges under Relaxed Electroneutrality Boundary Conditions
title_sort mathematical analysis on current voltage relations via classical poisson nernst planck systems with nonzero permanent charges under relaxed electroneutrality boundary conditions
topic PNP
permanent charges
I–V relations
critical potentials
boundary layers
url https://www.mdpi.com/2077-0375/13/2/131
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AT lijunzhang mathematicalanalysisoncurrentvoltagerelationsviaclassicalpoissonnernstplancksystemswithnonzeropermanentchargesunderrelaxedelectroneutralityboundaryconditions
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