New insights into fibrosis from the ECM degradation perspective: the macrophage-MMP-ECM interaction

New insights into fibrosis from the ECM degradation perspective: the macrophage-MMP-ECM interaction

Abstract Fibrosis is a pathological feature of a variety of chronic inflammatory diseases that can affect almost all organs, which can cause severe consequences and even lead to death. Fibrosis is characterized by the excessive accumulation of extracellular matrix (ECM) due to disruption of the bala...

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Bibliographic Details
Main Authors: Xiangyu Zhao, Jiayin Chen, Hongxiang Sun, Yao Zhang, Duowu Zou
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Cell & Bioscience
Subjects:
Fibrosis
Extracellular matrix
Macrophage
Matrix metalloprotease
Matricryptin
Online Access:https://doi.org/10.1186/s13578-022-00856-w

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