The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies
Abstract Background The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations. The role of abdominal obesity in the metabolic differences between the two populatio...
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| Format: | Article |
| Language: | English |
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BMC
2020-01-01
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| Series: | Diabetology & Metabolic Syndrome |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13098-019-0503-1 |
| _version_ | 1818411134314610688 |
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| author | Fathimah S. Sigit Dicky L. Tahapary Stella Trompet Erliyani Sartono Ko Willems van Dijk Frits R. Rosendaal Renée de Mutsert |
| author_facet | Fathimah S. Sigit Dicky L. Tahapary Stella Trompet Erliyani Sartono Ko Willems van Dijk Frits R. Rosendaal Renée de Mutsert |
| author_sort | Fathimah S. Sigit |
| collection | DOAJ |
| description | Abstract Background The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations. The role of abdominal obesity in the metabolic differences between the two populations is poorly understood. Objectives Our objectives were to estimate the prevalence of metabolic syndrome and the relative contribution of its components in the Indonesian and the Dutch population, as well as to examine the associations of overall and abdominal obesity with metabolic syndrome. Methods In this cross-sectional study of middle-aged adults in the Netherlands Epidemiology of Obesity Study (n = 6602) and the Indonesian National Health Surveillance (n = 10,575), metabolic syndrome was defined by the unified IDF and AHA/NHLBI criteria. We performed logistic and linear regressions to examine associations of BMI and waist circumference with the metabolic syndrome, mutually adjusted for waist circumference and BMI. Results The prevalence of metabolic syndrome was 28% and 46% in Indonesian men and women, and 36% and 24% in Dutch men and women. The most prominent components were hypertension (61%) and hyperglycemia (51%) in the Indonesian, and hypertension (62%) and abdominal obesity (40%) in the Dutch population. Per SD in BMI and waist circumference, odds ratios (ORs, 95% CI) of metabolic syndrome were 1.5 (1.3–1.8) and 2.3 (1.9–2.7) in Indonesian men and 1.7 (1.2–2.5) and 2.9 (2.1–4.1) in Dutch men. The ORs of metabolic syndrome were 1.4 (1.2–1.6) and 2.3 (2.0–2.7) in Indonesian women and 1.0 (0.8–1.3) and 4.2 (3.2–5.4) in Dutch women. Conclusion More Indonesian women than men have metabolic syndrome, whereas the opposite is true for the Dutch population. In both the Indonesian and the Dutch populations, hypertension is the primary contributor to the prevalence of metabolic syndrome. In both populations, abdominal adiposity was more strongly associated with metabolic syndrome than overall adiposity. |
| first_indexed | 2024-12-14T10:26:35Z |
| format | Article |
| id | doaj.art-e6f50f2bdd8648ed8ce350c4e7f3d3e9 |
| institution | Directory Open Access Journal |
| issn | 1758-5996 |
| language | English |
| last_indexed | 2024-12-14T10:26:35Z |
| publishDate | 2020-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Diabetology & Metabolic Syndrome |
| spelling | doaj.art-e6f50f2bdd8648ed8ce350c4e7f3d3e92022-12-21T23:06:18ZengBMCDiabetology & Metabolic Syndrome1758-59962020-01-0112111110.1186/s13098-019-0503-1The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studiesFathimah S. Sigit0Dicky L. Tahapary1Stella Trompet2Erliyani Sartono3Ko Willems van Dijk4Frits R. Rosendaal5Renée de Mutsert6Department of Clinical Epidemiology, Leiden University Medical CenterMetabolic, Cardiovascular, and Aging Cluster, The Indonesian Medical Education and Research Institute, Faculty of Medicine-Universitas IndonesiaDepartment of Internal Medicine, Leiden University Medical CenterDepartment of Parasitology, Leiden University Medical CenterDepartment of Internal Medicine, Leiden University Medical CenterDepartment of Clinical Epidemiology, Leiden University Medical CenterDepartment of Clinical Epidemiology, Leiden University Medical CenterAbstract Background The prevalence of metabolic syndrome varies among populations with different ethnicities. Asian populations develop metabolic complications at lower amounts of adiposity than western populations. The role of abdominal obesity in the metabolic differences between the two populations is poorly understood. Objectives Our objectives were to estimate the prevalence of metabolic syndrome and the relative contribution of its components in the Indonesian and the Dutch population, as well as to examine the associations of overall and abdominal obesity with metabolic syndrome. Methods In this cross-sectional study of middle-aged adults in the Netherlands Epidemiology of Obesity Study (n = 6602) and the Indonesian National Health Surveillance (n = 10,575), metabolic syndrome was defined by the unified IDF and AHA/NHLBI criteria. We performed logistic and linear regressions to examine associations of BMI and waist circumference with the metabolic syndrome, mutually adjusted for waist circumference and BMI. Results The prevalence of metabolic syndrome was 28% and 46% in Indonesian men and women, and 36% and 24% in Dutch men and women. The most prominent components were hypertension (61%) and hyperglycemia (51%) in the Indonesian, and hypertension (62%) and abdominal obesity (40%) in the Dutch population. Per SD in BMI and waist circumference, odds ratios (ORs, 95% CI) of metabolic syndrome were 1.5 (1.3–1.8) and 2.3 (1.9–2.7) in Indonesian men and 1.7 (1.2–2.5) and 2.9 (2.1–4.1) in Dutch men. The ORs of metabolic syndrome were 1.4 (1.2–1.6) and 2.3 (2.0–2.7) in Indonesian women and 1.0 (0.8–1.3) and 4.2 (3.2–5.4) in Dutch women. Conclusion More Indonesian women than men have metabolic syndrome, whereas the opposite is true for the Dutch population. In both the Indonesian and the Dutch populations, hypertension is the primary contributor to the prevalence of metabolic syndrome. In both populations, abdominal adiposity was more strongly associated with metabolic syndrome than overall adiposity.https://doi.org/10.1186/s13098-019-0503-1Metabolic syndromeAbdominal obesityBMIWaist circumference |
| spellingShingle | Fathimah S. Sigit Dicky L. Tahapary Stella Trompet Erliyani Sartono Ko Willems van Dijk Frits R. Rosendaal Renée de Mutsert The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies Diabetology & Metabolic Syndrome Metabolic syndrome Abdominal obesity BMI Waist circumference |
| title | The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies |
| title_full | The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies |
| title_fullStr | The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies |
| title_full_unstemmed | The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies |
| title_short | The prevalence of metabolic syndrome and its association with body fat distribution in middle-aged individuals from Indonesia and the Netherlands: a cross-sectional analysis of two population-based studies |
| title_sort | prevalence of metabolic syndrome and its association with body fat distribution in middle aged individuals from indonesia and the netherlands a cross sectional analysis of two population based studies |
| topic | Metabolic syndrome Abdominal obesity BMI Waist circumference |
| url | https://doi.org/10.1186/s13098-019-0503-1 |
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